Daniel Castano-Diez
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Explore the profile of Daniel Castano-Diez including associated specialties, affiliations and a list of published articles.
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41
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1803
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Recent Articles
1.
Vivas-Lago A, Castano-Diez D
Sci Rep
. 2025 Feb;
15(1):5501.
PMID: 39953118
This study introduces Ice Finder, a novel tool for quantifying crystalline ice in cryo-electron tomography, addressing a critical gap in existing methodologies. We present the first application of the meta-learning...
2.
Coray R, Navarro P, Scaramuzza S, Stahlberg H, Castano-Diez D
Structure
. 2024 Jul;
32(10):1808-1819.e4.
PMID: 39079528
With the advent of modern technologies for cryo-electron tomography (cryo-ET), high-quality tilt series are more rapidly acquired than processed and analyzed. Thus, a robust and fast-automated alignment for batch processing...
3.
Lopez-Robles C, Scaramuzza S, Astorga-Simon E, Ishida M, Williamson C, Banos-Mateos S, et al.
Nat Struct Mol Biol
. 2023 Jun;
30(7):958-969.
PMID: 37322239
Recycling of membrane proteins enables the reuse of receptors, ion channels and transporters. A key component of the recycling machinery is the endosomal sorting complex for promoting exit 1 (ESCPE-1),...
4.
HIV-2 Immature Particle Morphology Provides Insights into Gag Lattice Stability and Virus Maturation
Talledge N, Yang H, Shi K, Coray R, Yu G, Arndt W, et al.
J Mol Biol
. 2023 May;
435(15):168143.
PMID: 37150290
Retrovirus immature particle morphology consists of a membrane enclosed, pleomorphic, spherical and incomplete lattice of Gag hexamers. Previously, we demonstrated that human immunodeficiency virus type 2 (HIV-2) immature particles possess...
5.
Zivanov J, Oton J, Ke Z, von Kugelgen A, Pyle E, Qu K, et al.
Elife
. 2022 Dec;
11.
PMID: 36468689
We present a new approach for macromolecular structure determination from multiple particles in electron cryo-tomography (cryo-ET) data sets. Whereas existing subtomogram averaging approaches are based on 3D data models, we...
6.
De Rossi P, Lewis A, Furrer J, De Vos L, Demeter T, Zbinden A, et al.
EMBO Rep
. 2021 Nov;
22(12):e53877.
PMID: 34806807
Morphologically distinct TDP-43 aggregates occur in clinically different FTLD-TDP subtypes, yet the mechanism of their emergence and contribution to clinical heterogeneity are poorly understood. Several lines of evidence suggest that...
7.
Scaramuzza S, Castano-Diez D
PLoS Biol
. 2021 Aug;
19(8):e3001318.
PMID: 34437529
Subtomogram averaging (STA) is a powerful image processing technique in electron tomography used to determine the 3D structure of macromolecular complexes in their native environments. It is a fast growing...
8.
De La Mora E, Dezi M, Di Cicco A, Bigay J, Gautier R, Manzi J, et al.
Nat Commun
. 2021 Jun;
12(1):3459.
PMID: 34103503
Membrane contact sites (MCS) are subcellular regions where two organelles appose their membranes to exchange small molecules, including lipids. Structural information on how proteins form MCS is scarce. We designed...
9.
Syntychaki A, Rima L, Schmidli C, Stohler T, Bieri A, Sutterlin R, et al.
J Proteome Res
. 2019 Jul;
18(9):3521-3531.
PMID: 31355640
Proteins are involved in all tasks of life, and their characterization is essential to understand the underlying mechanisms of biological processes. We present a method called "differential visual proteomics" geared...
10.
Leigh K, Navarro P, Scaramuzza S, Chen W, Zhang Y, Castano-Diez D, et al.
Methods Cell Biol
. 2019 Jul;
152:217-259.
PMID: 31326022
Cryo-electron tomography (cryo-ET) allows three-dimensional (3D) visualization of frozen-hydrated biological samples, such as protein complexes and cell organelles, in near-native environments at nanometer scale. Protein complexes that are present in...