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Daniel C Bartos

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Citations 552
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Recent Articles
1.
Kekenes-Huskey P, Burgess D, Sun B, Bartos D, Rozmus E, Anderson C, et al.
Int J Mol Sci . 2022 Jul; 23(13). PMID: 35806392
The electrocardiogram (ECG) empowered clinician scientists to measure the electrical activity of the heart noninvasively to identify arrhythmias and heart disease. Shortly after the standardization of the 12-lead ECG for...
2.
Bartos D, Morotti S, Ginsburg K, Grandi E, Bers D
J Physiol . 2016 Dec; 595(7):2253-2268. PMID: 28008618
Key Points: [Ca ] enhanced rabbit ventricular slowly activating delayed rectifier K current (I ) by negatively shifting the voltage dependence of activation and slowing deactivation, similar to perfusion of...
3.
Grandi E, Sanguinetti M, Bartos D, Bers D, Chen-Izu Y, Chiamvimonvat N, et al.
J Physiol . 2016 Nov; 595(7):2209-2228. PMID: 27861921
This paper is the outcome of the fourth UC Davis Systems Approach to Understanding Cardiac Excitation-Contraction Coupling and Arrhythmias Symposium, a biannual event that aims to bring together leading experts...
4.
Ackerman J, Bartos D, Kapplinger J, Tester D, Delisle B, Ackerman M
Mayo Clin Proc . 2016 Nov; PMID: 27810088
We illustrate the work necessary to reverse course after identification of a KCNQ1 variant interpreted erroneously as causing long QT syndrome (LQTS) and to identify the true cause of a...
5.
Bartos D, Grandi E, Ripplinger C
Compr Physiol . 2015 Jul; 5(3):1423-64. PMID: 26140724
Optimal cardiac function depends on proper timing of excitation and contraction in various regions of the heart, as well as on appropriate heart rate. This is accomplished via specialized electrical...
6.
Schroder E, Burgess D, Zhang X, Lefta M, Smith J, Patwardhan A, et al.
Heart Rhythm . 2015 Feb; 12(6):1306-14. PMID: 25701773
Background: Sudden cardiac death (SCD) follows a diurnal variation. Data suggest the timing of SCD is influenced by circadian (~24-hour) changes in neurohumoral and cardiomyocyte-specific regulation of the heart's electrical...
7.
Sato D, Bartos D, Ginsburg K, Bers D
Biophys J . 2014 Sep; 107(6):1313-7. PMID: 25229139
The diastolic membrane potential (Vm) can be hyperpolarized or depolarized by various factors such as hyperkalemia or hypokalemia in the long term, or by delayed afterdepolarizations in the short term....
8.
Bartos D, Giudicessi J, Tester D, Ackerman M, Ohno S, Horie M, et al.
Heart Rhythm . 2013 Nov; 11(3):459-68. PMID: 24269949
Background: Type 1 long QT syndrome (LQT1) is caused by loss-of-function mutations in the KCNQ1-encoded Kv7.1 channel that conducts the slowly activating component of the delayed rectifier K(+) current (IKs)....
9.
Smith J, Reloj A, Nataraj P, Bartos D, Schroder E, Moss A, et al.
Am J Physiol Cell Physiol . 2013 Jul; 305(9):C919-30. PMID: 23864605
KCNH2 encodes Kv11.1 and underlies the rapidly activating delayed rectifier K(+) current (IKr) in the heart. Loss-of-function KCNH2 mutations cause the type 2 long QT syndrome (LQT2), and most LQT2-linked...
10.
Crotti L, Tester D, White W, Bartos D, Insolia R, Besana A, et al.
JAMA . 2013 Apr; 309(14):1473-82. PMID: 23571586
Importance: Intrauterine fetal death or stillbirth occurs in approximately 1 out of every 160 pregnancies and accounts for 50% of all perinatal deaths. Postmortem evaluation fails to elucidate an underlying...