Daniel Burgstaller
Overview
Explore the profile of Daniel Burgstaller including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
218
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Recent Articles
1.
Steppert P, Mosor M, Stanek L, Burgstaller D, Palmberger D, Preinsperger S, et al.
Vaccine
. 2022 Jan;
40(9):1323-1333.
PMID: 35094870
Purification of very large and complex, enveloped viruses, such as measles virus is very challenging, it must be performed in a closed system because the final product cannot be sterile...
2.
Satzer P, Burgstaller D, Krepper W, Jungbauer A
Eng Life Sci
. 2020 Sep;
20(3-4):67-78.
PMID: 32874171
Protein and in particular antibody precipitation by PEG is a cost-effective alternative for the first capture step. The 3D structure of precipitates has a large impact on the process parameters...
3.
Krepper W, Burgstaller D, Jungbauer A, Satzer P
Biotechnol Prog
. 2019 Oct;
36(2):e2928.
PMID: 31622530
Antibodies of the IgG2 subclass were captured from the clarified cell culture fluid either by protein A chromatography or by polyethylene glycol precipitation. The captured intermediates were stored as neutralized...
4.
Burgstaller D, Jungbauer A, Satzer P
Biotechnol Bioeng
. 2019 Jan;
116(5):1053-1065.
PMID: 30636284
Continuous precipitation is a new unit operation for the continuous capture of antibodies. The capture step is based on continuous precipitation with PEG6000 and Zn in a tubular reactor integrated...
5.
Burgstaller D, Krepper W, Haas J, Maszelin M, Mohoric J, Pajnic K, et al.
J Chem Technol Biotechnol
. 2018 Jul;
93(7):1881-1890.
PMID: 30008503
Background: Integrated continuous production technology is of great interest in biopharmaceutical industry. Efficient, flexible and cost effective methods for continuous cell removal have to be developed, before a fully continuous...
6.
Steppert P, Burgstaller D, Klausberger M, Tover A, Berger E, Jungbauer A
J Chromatogr A
. 2017 Jan;
1487:89-99.
PMID: 28110946
The rapid quantification of enveloped virus-like particles (VLPs) requires orthogonal methods to obtain reliable results. Three methods-nanoparticle tracking analysis (NTA), size-exclusion HPLC (SE-HPLC) with UV detection, and detection with multi-angle...
7.
Steppert P, Burgstaller D, Klausberger M, Kramberger P, Tover A, Berger E, et al.
J Sep Sci
. 2016 Dec;
40(4):979-990.
PMID: 27928907
The downstream processing of enveloped virus-like particles is very challenging because of the biophysical and structural similarity between correctly assembled particles and contaminating vesicular particles present in the feedstock. We...
8.
Steppert P, Burgstaller D, Klausberger M, Berger E, Pereira Aguilar P, Schneider T, et al.
J Chromatogr A
. 2016 Jun;
1455:93-101.
PMID: 27286649
Enveloped virus-like particles (VLPs) are increasingly used as vaccines and immunotherapeutics. Frequently, very time consuming density gradient centrifugation techniques are used for purification of VLPs. However, the progress towards optimized...
9.
Kittl R, Kracher D, Burgstaller D, Haltrich D, Ludwig R
Biotechnol Biofuels
. 2012 Oct;
5(1):79.
PMID: 23102010
Unlabelled: Background: Recent studies demonstrate that enzymes from the glycosyl hydrolase family 61 (GH61) show lytic polysaccharide monooxygenase (PMO) activity. Together with cellobiose dehydrogenase (CDH) an enzymatic system capable of...