Alois Jungbauer
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Explore the profile of Alois Jungbauer including associated specialties, affiliations and a list of published articles.
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246
Citations
1682
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Recent Articles
1.
Pons Royo M, Jungbauer A
Prep Biochem Biotechnol
. 2025 Mar;
:1-20.
PMID: 40084924
Downstream processing continues to face significant bottlenecks due to current purification technologies and improvements in upstream. Chromatography systems have been the primary method for purification due to their high yields...
2.
Mayer V, Steiner F, Jungbauer A, Pereira Aguilar P
J Chromatogr A
. 2024 Nov;
1738:465470.
PMID: 39488125
Highly purified virus preparations are essential for accurate activity and potency determination. This requires simple and efficient purification methods, especially in the early stages of research and development. While heparin...
3.
Guzman Ruiz L, Zollner A, Hoxie I, Kuchler J, Hausjell C, Mesurado T, et al.
Vaccine
. 2024 Aug;
42(24):126270.
PMID: 39197219
Current influenza virus vaccines poorly display key neuraminidase (NA) epitopes and do not robustly induce NA-reactive antibodies; instead, they focus on the induction of hemagglutinin (HA)-reactive antibodies. Next-generation influenza vaccines...
4.
Mozgovicz M, Lingg N, Bresolin I, Schaufler T, Jungbauer A
Prep Biochem Biotechnol
. 2024 Aug;
55(2):217-222.
PMID: 39091236
Advances in affinity chromatography now make it possible to analyze immunoglobulin G from plasma and its fractions with a simple chromatographic method. Ligands derived from camelid antibodies have been developed...
5.
Lima Leite A, Nascimento T, da Cunha M, Mehari Y, Berger E, Scheich D, et al.
Int J Biol Macromol
. 2024 Jul;
275(Pt 2):133581.
PMID: 38960262
Secretory immunoglobulin A [sIgA] is a promising candidate for enteric therapeutics applications, and several sIgA-based constructs are currently being developed by groups utilizing clarified Chinese hamster ovary [CHO] cell culture...
6.
Tscheliessnig R, Silva G, Plewka J, Jakob L, Lichtenegger H, Jungbauer A, et al.
J Chromatogr A
. 2024 Jun;
1730:465102.
PMID: 38941799
Staphylococcal protein-A affinity chromatography has been optimized for antibody purification, achieving a current capacity of up to 90 mg/ml in packed bed. The morphology of the particles, the number of...
7.
Guzman Ruiz L, Zollner A, Hoxie I, Arcalis E, Krammer F, Klausberger M, et al.
Front Immunol
. 2024 Jun;
15:1425842.
PMID: 38915410
Vaccination against influenza virus can reduce the risk of influenza by 40% to 60%, they rely on the production of neutralizing antibodies specific to influenza hemagglutinin (HA) ignoring the neuraminidase...
8.
Lali N, Tsiatsiani L, Elffrink W, Kokke B, Satzer P, Dirksen E, et al.
J Chromatogr A
. 2024 May;
1728:464995.
PMID: 38805895
Fluorescently labeled antibodies are widely used to visualize the adsorption process in protein chromatography using confocal laser scanning microscopy (CLSM), but also as a tracer for determination of residence time...
9.
Jungbauer A, Ferreira G, Butler M, DCosta S, Brower K, Rayat A, et al.
Biotechnol Bioeng
. 2024 May;
121(8):2524-2541.
PMID: 38795025
Governments and biopharmaceutical organizations aggressively leveraged expeditious communication capabilities, decision models, and global strategies to make a COVID-19 vaccine happen within a period of 12 months. This was an unusual...
10.
Chen Y, Recanati G, De Mathia F, Lin D, Jungbauer A
Biotechnol Bioeng
. 2024 Mar;
121(6):1876-1888.
PMID: 38494789
Regulatory authorities recommend using residence time distribution (RTD) to address material traceability in continuous manufacturing. Continuous virus filtration is an essential but poorly understood step in biologics manufacturing in respect...