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Daniel B Werz

Explore the profile of Daniel B Werz including associated specialties, affiliations and a list of published articles. Areas
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Articles 177
Citations 1741
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Recent Articles
1.
Oliver G, Kolb S, George M, Werz D
Angew Chem Int Ed Engl . 2025 Feb; :e202424823. PMID: 39936835
Herein we report (3+2)-cycloaddition reactions of halogenated donor-acceptor cyclopropanes (HDACs) as surrogates for donor-acceptor cyclopropenes. Upon reaction with a variety of 2π-components, cycloaddition followed by elimination generates the unsaturated five-membered...
2.
Rottger S, Patalag L, von Koller H, Werthmuller J, Birk A, Butschke B, et al.
Org Lett . 2024 Dec; 27(1):68-72. PMID: 39689292
facile access to -heteroaryl-fused bis-BODIPY scaffolds has been developed. A BODIPY dimer with an α,α-amine linker serves as a starting material to obtain pyrrole- and pyridine-fused BODIPYs, either by direct...
3.
Biswas A, Kolb S, Rottger S, Das A, Patalag L, Dey P, et al.
Angew Chem Int Ed Engl . 2024 Dec; 64(5):e202416472. PMID: 39655963
An established concept to create radical intermediates is photoexcitation of a catalyst to a higher energy intermediate, subsequently leading to a photoinduced electron transfer (PET) with a reaction partner. The...
4.
George M, Mindner J, Wittmer S, Knyazev D, Werz D
Chemistry . 2024 Dec; 31(9):e202404099. PMID: 39624949
A (3+3)-cycloaddition to afford 2-azabiyclo[3.1.1]heptanes was realized by reacting highly strained aryl bicyclo[1.1.0]butane (BCBs) carboxylates with tosylated aziridines. Under Sc(OTf) catalysis the transformation proceeded smoothly under mild conditions to the...
5.
Kalvani P, Werz D
Org Lett . 2024 Nov; 26(48):10404-10408. PMID: 39571182
In this report, we describe Pd-catalyzed cascade reactions in which two internal alkynes undergo two -carbocarbonation reactions, leading to new carbon-carbon bonds across the emerging double bonds. The resulting vinyl...
6.
Lange M, Werz D
Org Lett . 2024 Nov; 26(46):9871-9876. PMID: 39513747
In this report, we describe a simple method for the synthesis of 2-aryl-2-vinyl-cyclobutanones through the reaction of in situ generated cyclopropanones and cinnamylsulfonium ylides, representing an example of a formal...
7.
Ali W, Oliver G, Werz D, Maiti D
Chem Soc Rev . 2024 Aug; 53(19):9904-9953. PMID: 39212454
Differentiating between two highly similar C-H bonds in a given molecule remains a fundamental challenge in synthetic organic chemistry. Directing group assisted strategies for the functionalisation of proximal C-H bonds...
8.
Teja C, Kolb S, Colonna P, Grover J, Garcia-Argote S, Lahiri G, et al.
Angew Chem Int Ed Engl . 2024 Aug; 63(48):e202410162. PMID: 39109510
Deuterated and tritiated analogs of drugs are valuable compounds for pharmaceutical and medicinal chemistry. In this work, we present a novel hydrogen isotope exchange reaction of drugs using non-directed homogeneous...
9.
Kolb S, Werz D
Angew Chem Int Ed Engl . 2024 May; 63(46):e202316037. PMID: 38695672
The recently reported electrochemical, organo-mediator enabled deuteration of styrenes, a reaction referred to as "electrochemical deuterium atom transfer", differs mechanistically from reported direct electrochemical hydrogenations/deuterations only by a mediated, homogeneous...
10.
Rottger S, Patalag L, Hasenmaile F, Milbrandt L, Butschke B, Jones P, et al.
Org Lett . 2024 Apr; 26(15):3020-3025. PMID: 38564714
A convergent route toward nitrogen-bridged BODIPY oligomers has been developed. The synthetic key step is a Buchwald-Hartwig cross-coupling reaction of an α-amino-BODIPY and the respective halide. Not only does the...