Daniel B McClatchy
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Explore the profile of Daniel B McClatchy including associated specialties, affiliations and a list of published articles.
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52
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1133
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Recent Articles
1.
McClatchy D, Garrett P, Jung T, Diedrich J, Yates 3rd J
J Proteome Res
. 2024 Nov;
23(12):5487-5497.
PMID: 39579148
Biorthogonal noncanonical amino acid tagging is a labeling strategy that covalently adds a biotin-alkyne (BA) to methionine analogs via a click reaction. When methionine analogs are incorporated into a proteome,...
2.
Son A, Kim H, Diedrich J, Bamberger C, McClatchy D, Lipton S, et al.
Nat Commun
. 2024 Oct;
15(1):9310.
PMID: 39468068
Mass spectrometry-based methods can provide a global expression profile and structural readout of proteins in complex systems. Preserving the in vivo conformation of proteins in their innate state is challenging...
3.
Lev-Ram V, Lemieux S, Deerinck T, Bushong E, Perez A, Pritchard D, et al.
Cells
. 2024 Oct;
13(19.
PMID: 39404392
Perineuronal nets (PNNs), a specialized form of extra cellular matrix (ECM), surround numerous neurons in the CNS and allow synaptic connectivity through holes in its structure. We hypothesize that PNNs...
4.
Gamaleldin M, Yu N, Diedrich J, Ma Y, Wienand A, McClatchy D, et al.
J Proteome Res
. 2024 Oct;
23(11):4878-4895.
PMID: 39374426
Direct detection of biotinylated proteins (DiDBiT) is a proteomic method that can enrich and detect newly synthesized proteins (NSPs) labeled with bio-orthogonal amino acids with 20-fold improved detectability compared to...
5.
McClatchy D, Yates 3rd J
bioRxiv
. 2024 Jul;
PMID: 39071280
BONCAT (Biorthogonal noncanonical amino acid tagging) is a labeling strategy that covalently adds a biotin-alkyne (BA) to methionine analogs via a click reaction. When methionine analogs are incorporated into a...
6.
Xie Y, Wang R, McClatchy D, Ma Y, Diedrich J, Sanchez-Alavez M, et al.
bioRxiv
. 2024 Jul;
PMID: 38979362
Neurons dynamically regulate their proteome in response to sensory input, a key process underlying experience-dependent plasticity. We characterized the visual experience-dependent nascent proteome within a brief, defined time window after...
7.
8.
Yang D, Wang Y, Qi T, Zhang X, Shen L, Ma J, et al.
Neuron
. 2024 Jan;
112(6):959-971.e8.
PMID: 38266644
For decades, the expression of immediate early genes (IEGs) such as FOS has been the most widely used molecular marker representing neuronal activation. However, to date, there is no equivalent...
9.
McClatchy D, Powell S, Yates J
bioRxiv
. 2024 Jan;
PMID: 38168169
Genetic analyses of Schizophrenia (SCZ) patients have identified thousands of risk factors. In silico protein-protein interaction (PPI) network analysis has provided strong evidence that disrupted PPI networks underlie SCZ pathogenesis....
10.
Kawata M, McClatchy D, Diedrich J, Olmer M, Johnson K, Yates J, et al.
JCI Insight
. 2023 Sep;
8(17).
PMID: 37681413
Osteoarthritis (OA) is the most common joint disorder, and disease-modifying OA drugs (DMOADs) represent a major need in OA management. Krüppel-like factor 4 (KLF4) is a central transcription factor upregulating...