Dana M McTigue
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Explore the profile of Dana M McTigue including associated specialties, affiliations and a list of published articles.
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61
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2852
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Recent Articles
1.
Li J, Farrow M, Ibrahim K, McTigue D, Kramer J, Tong B, et al.
Spinal Cord
. 2024 Jul;
62(8):486-494.
PMID: 38961159
Study Design: Secondary analysis of a randomized, multi-center, placebo-controlled study(Sygen®). Objectives: To evaluate racial differences in serological markers in individuals with spinal cord injury(SCI) across the first year of injury....
2.
Goodus M, Alfredo A, Carson K, Dey P, Pukos N, Schwab J, et al.
Exp Neurol
. 2024 Jun;
379:114847.
PMID: 38852834
Impaired sensorimotor functions are prominent complications of spinal cord injury (SCI). A clinically important but less obvious consequence is development of metabolic syndrome (MetS), including increased adiposity, hyperglycemia/insulin resistance, and...
3.
DiSabato D, Marion C, Mifflin K, Alfredo A, Rodgers K, Kigerl K, et al.
Eur J Immunol
. 2023 Oct;
54(1):e2250274.
PMID: 37822141
Spinal cord injury (SCI) affects hundreds of thousands of people in the United States, and while some effects of the injury are broadly recognized (deficits to locomotion, fine motor control,...
4.
Li Y, Drabison T, Nepal M, Ho R, Leblanc A, Gibson A, et al.
JCI Insight
. 2023 Jun;
8(14).
PMID: 37347545
Vincristine is a widely used chemotherapeutic drug for the treatment of multiple malignant diseases that causes a dose-limiting peripheral neurotoxicity. There is no clinically effective preventative treatment for vincristine-induced sensory...
5.
Pukos N, Marion C, Arnold W, Noble B, Popovich P, McTigue D
Glia
. 2023 May;
71(9):2096-2116.
PMID: 37208933
Our prior work examining endogenous repair after spinal cord injury (SCI) in mice revealed that large numbers of new oligodendrocytes (OLs) are generated in the injured spinal cord, with peak...
6.
Brennan F, Li Y, Wang C, Ma A, Guo Q, Li Y, et al.
Nat Commun
. 2022 Jul;
13(1):4096.
PMID: 35835751
Traumatic spinal cord injury (SCI) triggers a neuro-inflammatory response dominated by tissue-resident microglia and monocyte derived macrophages (MDMs). Since activated microglia and MDMs are morphologically identical and express similar phenotypic...
7.
Otto L, Russart K, Kulkarni P, McTigue D, Ferris C, Pyter L
Front Oncol
. 2022 Apr;
12:798704.
PMID: 35402248
Breast cancer is one of the most common diseases in the United States with 1 in 8 women developing the disease in her lifetime. Women who develop breast cancer are...
8.
Faw T, Lakhani B, Schmalbrock P, Knopp M, Lohse K, Kramer J, et al.
Exp Neurol
. 2021 Aug;
346:113853.
PMID: 34464653
Experience-dependent white matter plasticity offers new potential for rehabilitation-induced recovery after neurotrauma. This first-in-human translational experiment combined myelin water imaging in humans and genetic fate-mapping of oligodendrocyte lineage cells in...
9.
Sauerbeck A, Goldstein E, Alfredo A, Norenberg M, Marcillo A, McTigue D
Sci Rep
. 2021 Jun;
11(1):11720.
PMID: 34083630
Synucleinopathies are neurodegenerative diseases in which α-synuclein protein accumulates in neurons and glia. In these diseases, α-synuclein forms dense intracellular aggregates that are disease hallmarks and actively contribute to tissue...
10.
Goodus M, Carson K, Sauerbeck A, Dey P, Alfredo A, Popovich P, et al.
Exp Neurol
. 2021 May;
342:113725.
PMID: 33933462
The current high obesity rates mean that neurological injuries are increasingly sustained on a background of systemic pathology, including liver inflammation, which likely has a negative impact on outcomes. Because...