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Dan K Nelson

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Recent Articles
1.
Numanami H, Koyama S, Nelson D, Hoyt J, Freels J, Habib M, et al.
Am J Respir Cell Mol Biol . 2003 May; 29(5):613-9. PMID: 12738688
Smoking is associated with lung inflammation and a protease-antiprotease imbalance. We previously reported that cigarette smoke extract (CSE) stimulates human lung fibroblasts to release chemotactic cytokines. We hypothesized that serine...
2.
Numanami H, Koyama S, Sato E, Haniuda M, Nelson D, Hoyt J, et al.
Am J Physiol Lung Cell Mol Physiol . 2003 Apr; 284(5):L882-90. PMID: 12676771
Chemotactic chemokines can be released from lung fibroblasts in response to interleukin (IL)-1beta and tumor necrosis factor (TNF)-alpha. An imbalance between proteases and antiproteases has been observed at inflammatory sites,...
3.
Numanami H, Nelson D, Hoyt J, Freels J, Habib M, Amano J, et al.
Am J Respir Cell Mol Biol . 2003 Mar; 29(2):239-44. PMID: 12626343
Peroxynitrite, formed by nitric oxide and superoxide, has been shown to nitrate and reduce the function of proinflammatory proteins such as interleukin (IL)-8, monocyte chemoattractant protein-1, and eotaxin, but in...
4.
Freels J, Nelson D, Hoyt J, Habib M, Numanami H, Lantz R, et al.
J Immunol . 2002 Oct; 169(8):4568-71. PMID: 12370394
Nitric oxide and superoxide form the unstable compound, peroxynitrite, which can nitrate proteins and compromise function of proinflammatory cytokines at sites of inflammation. Reduced function of proinflammatory proteins such as...