Damon B Bowe
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Explore the profile of Damon B Bowe including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
446
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Recent Articles
1.
Wu J, Bowe D, Sadlonova A, Whisenhunt T, Hu Y, Rustgi A, et al.
J Biol Chem
. 2014 Mar;
289(17):12168-12176.
PMID: 24616106
The Drosophila Groucho protein and its mammalian orthologues the transducin-like enhancers of split (TLEs) are critical transcriptional corepressors that repress Wnt and other signaling pathways. Although it is known that...
2.
Huang P, Ho S, Wang K, Roessler B, Zhang F, Hu Y, et al.
Am J Physiol Cell Physiol
. 2010 Dec;
300(3):C456-65.
PMID: 21178104
The protein O-linked β-N-acetylglucosamine (O-GlcNAc) modification plays an important role in skeletal muscle development and physiological function. In this study, bitransgenic mice were generated that overexpressed NCOAT(GK), an O-GlcNAcase-inactive spliced...
3.
Sadlonova A, Bowe D, Novak Z, Mukherjee S, Duncan V, Page G, et al.
Cancer Microenviron
. 2009 Mar;
2(1):9-21.
PMID: 19308679
Stromal fibroblasts influence the behavior of breast epithelial cells. Fibroblasts derived from normal breast (NAF) inhibit epithelial growth, whereas fibroblasts from breast carcinomas (CAF) have less growth inhibitory capacity and...
4.
Sadlonova A, Mukherjee S, Bowe D, Gault S, Dumas N, Van Tine B, et al.
Am J Pathol
. 2007 Feb;
170(3):1064-76.
PMID: 17322389
Stromal fibroblasts are important for normal breast homeostasis and regulation of epithelial growth; however, this regulatory function is altered during carcinogenesis. To study the role of fibroblasts in the development...
5.
Bowe D, Sadlonova A, Toleman C, Novak Z, Hu Y, Huang P, et al.
Mol Cell Biol
. 2006 Sep;
26(22):8539-50.
PMID: 16966374
Mechanisms controlling nuclear hormone receptors are a central question to mammalian developmental and disease processes. Herein, we show that a subtle increase in O-GlcNAc levels inhibits activation of nuclear hormone...
6.
Whisenhunt T, Yang X, Bowe D, Paterson A, Van Tine B, Kudlow J
Glycobiology
. 2006 Mar;
16(6):551-63.
PMID: 16505006
Although the knowledge that nuclear and cytoplasmic proteins are modified with N-acetylglucosamine has existed for decades, little has been shown as to its function until recently. There are now substantial...
7.
Sadlonova A, Novak Z, Johnson M, Bowe D, Gault S, Page G, et al.
Breast Cancer Res
. 2005 Jan;
7(1):R46-59.
PMID: 15642169
Background: Stromal fibroblasts associated with in situ and invasive breast carcinoma differ phenotypically from fibroblasts associated with normal breast epithelium, and these alterations in carcinoma-associated fibroblasts (CAF) may promote breast...
8.
Zhang F, Su K, Yang X, Bowe D, Paterson A, Kudlow J
Cell
. 2003 Dec;
115(6):715-25.
PMID: 14675536
The ubiquitin proteasome system classically selects its substrates for degradation by tagging them with ubiquitin. Here, we describe another means of controlling proteasome function in a global manner. The 26S...
9.
Bowe D, Kenney N, Adereth Y, Maroulakou I
Oncogene
. 2002 Jan;
21(2):291-8.
PMID: 11803472
Amplification and/or overexpression of the receptor tyrosine kinase HER2/Neu and the cell cycle regulatory gene cyclin D1 are frequently associated with human breast cancer. We studied the functional significance of...