Damian Tyler
Overview
Explore the profile of Damian Tyler including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
162
Followers
0
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Recent Articles
1.
Monga S, Valkovic L, Tyler D, Lygate C, Rider O, Myerson S, et al.
JACC Cardiovasc Imaging
. 2022 Dec;
15(12):2112-2126.
PMID: 36481080
Pressure overload in aortic stenosis (AS) encompasses both structural and metabolic remodeling and increases the risk of decompensation into heart failure. A major component of metabolic derangement in AS is...
2.
Sanchez-Heredia J, Olin R, Grist J, Wang W, Bogh N, Zhurbenko V, et al.
Magn Reson Med
. 2022 May;
88(3):1391-1405.
PMID: 35635156
Purpose: To develop a coil-based method to obtain accurate sensitivity profiles in C MRI at 3T from the endogenous Na. An eight-channel array is designed for C MR acquisitions. As...
3.
Carnicer R, Duglan D, Ziberna K, Recalde A, Reilly S, Simon J, et al.
Circ Res
. 2021 Jan;
128(5):585-601.
PMID: 33494625
Rationale: In diabetic patients, heart failure with predominant left ventricular (LV) diastolic dysfunction is a common complication for which there is no effective treatment. Oxidation of the NOS (nitric oxide...
4.
Marco-Rius I, Wright A, Hu D, Savic D, Miller J, Timm K, et al.
MAGMA
. 2020 Sep;
34(1):49-56.
PMID: 32910316
Objectives: To enhance detection of the products of hyperpolarized [2-C]dihydroxyacetone metabolism for assessment of three metabolic pathways in the liver in vivo. Hyperpolarized [2-C]DHAc emerged as a promising substrate to...
5.
Watson W, Miller J, Lewis A, Neubauer S, Tyler D, Rider O, et al.
Cardiovasc Diagn Ther
. 2020 Jul;
10(3):583-597.
PMID: 32695639
The heart has a massive adenosine triphosphate (ATP) requirement, produced from the oxidation of metabolic substrates such as fat and glucose. Magnetic resonance spectroscopy offers a unique opportunity to probe...
6.
Betts C, McClorey G, Healicon R, Hammond S, Manzano R, Muses S, et al.
Hum Mol Genet
. 2018 Oct;
28(3):396-406.
PMID: 30281092
Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin protein, leading to progressive muscle weakness and premature death due to respiratory and/or cardiac complications. Cardiac involvement is characterized by...
7.
Apps A, Lau J, Peterzan M, Neubauer S, Tyler D, Rider O
Heart
. 2018 Apr;
104(18):1484-1491.
PMID: 29703741
Although non-invasive perfusion and viability imaging often provide the gateway to coronary revascularisation, current non-invasive imaging methods only report the surrogate markers of inducible hypoperfusion and presence or absence of...
8.
Slingo M, Cole M, Carr C, Curtis M, Dodd M, Giles L, et al.
Am J Physiol Heart Circ Physiol
. 2016 Jul;
311(3):H759-67.
PMID: 27422990
Hypoxia-inducible factor (HIF) appears to function as a global master regulator of cellular and systemic responses to hypoxia. HIF pathway manipulation is of therapeutic interest; however, global systemic upregulation of...
9.
Maesen B, Zeemering S, Afonso C, Eckstein J, Burton R, van Hunnik A, et al.
Circ Arrhythm Electrophysiol
. 2013 Aug;
6(5):967-75.
PMID: 23969531
Background: Anisotropy of conduction facilitates re-entry and is, therefore, a key determinant of the stability of atrial fibrillation (AF). Little is known about the effect of AF on atrial bundle...
10.
Rider O, Francis J, Ali M, Holloway C, Pegg T, Robson M, et al.
Circulation
. 2012 Feb;
125(12):1511-9.
PMID: 22368152
Background: Obesity is characterized by impaired cardiac energetics, which may play a role in the development of diastolic dysfunction and inappropriate shortness of breath. We assessed whether, in obesity, derangement...