Craig A Lygate
Overview
Explore the profile of Craig A Lygate including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
92
Citations
2026
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Tabish T, Hussain M, Zhu Y, Xu J, Huang W, Diotallevi M, et al.
Appl Phys Rev
. 2024 Oct;
11(3).
PMID: 39355510
Drug-eluting stents are commonly utilized for the treatment of coronary artery disease, where they maintain vessel patency and prevent restenosis. However, problems with prolonged vascular healing, late thrombosis, and neoatherosclerosis...
2.
Zervou S, McAndrew D, Lake H, Kuznecova E, Preece C, Davies B, et al.
J Mol Cell Cardiol
. 2024 Sep;
196:105-114.
PMID: 39276853
Improving energy provision in the failing heart by augmenting the creatine kinase (CK) system is a desirable therapeutic target. However, over-expression of the creatine transporter (CrT-OE) has shown that very...
3.
Lewis A, Dodd M, Sourdon J, Lygate C, Clarke K, Neubauer S, et al.
NMR Biomed
. 2024 Jul;
37(11):e5206.
PMID: 38994722
Obesity is associated with important changes in cardiac energetics and function, and an increased risk of adverse cardiovascular outcomes. Multi-nuclear MRS and MRI techniques have the potential to provide a...
4.
Tabish T, Crabtree M, Townley H, Winyard P, Lygate C
JACC Basic Transl Sci
. 2024 Jul;
9(5):691-709.
PMID: 38984042
A central paradigm of cardiovascular homeostasis is that impaired nitric oxide (NO) bioavailability results in a wide array of cardiovascular dysfunction including incompetent endothelium-dependent vasodilatation, thrombosis, vascular inflammation, and proliferation...
5.
Lygate C
Clin Sci (Lond)
. 2024 Apr;
138(8):491-514.
PMID: 38639724
The non-stop provision of chemical energy is of critical importance to normal cardiac function, requiring the rapid turnover of ATP to power both relaxation and contraction. Central to this is...
6.
Tabish T, Xu J, Campbell C, Abbas M, Myers W, Didwal P, et al.
Nitric Oxide
. 2024 Apr;
147:42-50.
PMID: 38631610
Nitric oxide (NO) donating drugs such as organic nitrates have been used to treat cardiovascular diseases for more than a century. These donors primarily produce NO systemically. It is however...
7.
Tabish T, Hussain M, Zervou S, Myers W, Tu W, Xu J, et al.
Redox Biol
. 2024 Apr;
72:103144.
PMID: 38613920
Nitric oxide (NO) is a key signalling molecule released by vascular endothelial cells that is essential for vascular health. Low NO bioactivity is associated with cardiovascular diseases, such as hypertension,...
8.
Tabish T, Zhu Y, Shukla S, Kadian S, Sangha G, Lygate C, et al.
Appl Phys Rev
. 2024 Jan;
10:041310.
PMID: 38229764
Nitric oxide (NO) signaling plays many pivotal roles impacting almost every organ function in mammalian physiology, most notably in cardiovascular homeostasis, inflammation, and neurological regulation. Consequently, the ability to make...
9.
Tabish T, Lygate C
Nanomedicine (Lond)
. 2023 Dec;
18(28):2101-2104.
PMID: 38059500
Tweetable abstract Mitochondria are increasingly a target for drug delivery in cardiovascular diseases. This editorial describes how a nanomedicine approach may improve drug potency and efficacy in a safe and...
10.
Measuring cardiomyocyte cellular characteristics in cardiac hypertrophy using diffusion-weighted MRI
Farzi M, Coveney S, Afzali M, Zdora M, Lygate C, Rau C, et al.
Magn Reson Med
. 2023 Jun;
90(5):2144-2157.
PMID: 37345727
Purpose: This paper presents a hierarchical modeling approach for estimating cardiomyocyte major and minor diameters and intracellular volume fraction (ICV) using diffusion-weighted MRI (DWI) data in ex vivo mouse hearts....