Dallas M Swallow
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Explore the profile of Dallas M Swallow including associated specialties, affiliations and a list of published articles.
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41
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1468
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Recent Articles
1.
Cohen C, Swallow D, Walker C
Ann Hum Genet
. 2024 Aug;
PMID: 39171584
Lactase persistence (LP) - the genetic trait that determines the continued expression of the enzyme lactase into adulthood - has undergone recent, rapid positive selection since the advent of animal...
2.
Lau W, Ali A, Maude H, Andrew T, Swallow D, Maniatis N
Genome Biol
. 2024 Jan;
25(1):7.
PMID: 38172955
Background: The cost-free increase in statistical power of using imputation to infer missing genotypes is undoubtedly appealing, but is it hazard-free? This case study of three type-2 diabetes (T2D) loci...
3.
Ali A, Liebert A, Lau W, Maniatis N, Swallow D
Ann Hum Genet
. 2021 Sep;
86(1):24-33.
PMID: 34523124
Although imputation of missing SNP results has been widely used in genetic studies, claims about the quality and usefulness of imputation have outnumbered the few studies that have questioned its...
4.
Ingram C, Ekong R, Ansari-Pour N, Bradman N, Swallow D
Pharmacogenomics J
. 2020 Jul;
21(1):47-59.
PMID: 32683419
Inter-individual variation of drug metabolising enzymes (DMEs) leads to variable efficacy of many drugs and even adverse drug responses. Consequently, it would be desirable to test variants of many DMEs...
5.
Montalva N, Adhikari K, Liebert A, Mendoza-Revilla J, Flores S, Mace R, et al.
Ann Hum Genet
. 2018 Sep;
83(1):11-22.
PMID: 30264486
The genetic trait of lactase persistence (LP) evolved as an adaptation to milking pastoralism in the Old World and is a well-known example of positive natural selection in humans. However,...
6.
Liebert A, Lopez S, Jones B, Montalva N, Gerbault P, Lau W, et al.
Hum Genet
. 2017 Oct;
136(11-12):1445-1453.
PMID: 29063188
The genetic trait of lactase persistence (LP) is associated with at least five independent functional single nucleotide variants in a regulatory region about 14 kb upstream of the lactase gene...
7.
Liebert A, Jones B, Danielsen E, Olsen A, Swallow D, Troelsen J
Ann Hum Genet
. 2016 Oct;
80(6):307-318.
PMID: 27714771
The genetic trait that allows intestinal lactase to persist into adulthood in some 35% of humans worldwide operates at the level of transcription, the effect being caused by cis-acting nucleotide...
8.
Swallow D, Troelsen J
Nat Struct Mol Biol
. 2016 Jun;
23(6):505-7.
PMID: 27273635
No abstract available.
9.
Jones B, Oljira T, Liebert A, Zmarz P, Montalva N, Tarekeyn A, et al.
Hum Genet
. 2015 Jun;
134(8):917-25.
PMID: 26054462
The genetic trait of lactase persistence is attributable to allelic variants in an enhancer region upstream of the lactase gene, LCT. To date, five different functional alleles, -13910*T, -13907*G, -13915*G,...
10.
Horsfall L, Hardy R, Wong A, Kuh D, Swallow D
J Hepatol
. 2014 Aug;
61(6):1344-51.
PMID: 25086287
Background & Aims: Bilirubin has potent antioxidant properties in vitro and raised serum levels have been associated with lower rates of respiratory disease. The enzyme uridine diphosphate glucuronosyltransferase polypeptide 1A1...