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Dalia H Abdelaziz

Explore the profile of Dalia H Abdelaziz including associated specialties, affiliations and a list of published articles. Areas
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Citations 194
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Recent Articles
1.
Tahir W, Abdulrahman B, Abdelaziz D, Thapa S, Walia R, Schatzl H
J Biol Chem . 2020 Jun; 295(33):11572-11583. PMID: 32561641
Prion diseases are fatal infectious neurodegenerative disorders in human and animals caused by misfolding of the cellular prion protein (PrP) into the pathological isoform PrP Elucidating the molecular and cellular...
2.
Thapa S, Abdelaziz D, Abdulrahman B, Schatzl H
Mol Neurobiol . 2020 Jan; 57(5):2206-2219. PMID: 31981074
Prion diseases are fatal infectious neurodegenerative disorders in human and animals caused by misfolding of the cellular prion protein (PrP) into the infectious isoform PrP. These diseases have the potential...
3.
Abdelaziz D, Thapa S, Abdulrahman B, Vankuppeveld L, Schatzl H
Biochem Biophys Res Commun . 2019 Dec; 523(2):423-428. PMID: 31874705
Prion diseases are fatal infectious neurodegenerative disorders in human and animals that are caused by misfolding of the cellular prion protein (PrP) into the infectious isoform PrP. No effective treatment...
4.
Abdelaziz D, Abdulrahman B, Gilch S, Schatzl H
Curr Opin Pharmacol . 2019 May; 44:46-52. PMID: 31096117
Prions use cellular machineries for autocatalytic propagation by conformational conversion of the cellular prion protein into the pathological isoform PrP. Autophagy is a basic cellular degradation and recycling machinery that...
5.
Abdelaziz D, Thapa S, Brandon J, Maybee J, Vankuppeveld L, McCorkell R, et al.
J Biol Chem . 2018 Nov; 293(51):19812-19822. PMID: 30397182
Chronic wasting disease (CWD) is a fatal neurodegenerative disease that affects cervids in North America and now Europe. No effective measures are available to control CWD. We hypothesized that active...
6.
Thapa S, Abdulrahman B, Abdelaziz D, Lu L, Ben Aissa M, Schatzl H
J Biol Chem . 2018 Aug; 293(41):16069-16082. PMID: 30154245
Prion diseases are fatal infectious neurodegenerative disorders in humans and other animals and are caused by misfolding of the cellular prion protein (PrP) into the pathological isoform PrP These diseases...
7.
Abdulrahman B, Abdelaziz D, Schatzl H
J Biol Chem . 2018 Apr; 293(23):8956-8968. PMID: 29700113
Prions are protein-based infectious agents that autocatalytically convert the cellular prion protein PrP to its pathological isoform PrP Subsequent aggregation and accumulation of PrP in nervous tissues causes several invariably...
8.
Abdelaziz D, Thapa S, Abdulrahman B, Lu L, Jain S, Schatzl H
Sci Rep . 2017 Sep; 7(1):10538. PMID: 28874781
Chronic wasting disease (CWD) is the most contagious prion disease. It is expanding rapidly in North America, was found recently in Europe, and the potential for transmission to humans cannot...
9.
Abdelaziz D, Gavrilin M, Akhter A, Caution K, Kotrange S, Abu Khweek A, et al.
J Biol Chem . 2010 Nov; 286(5):3203-8. PMID: 21097506
The ability of Legionella pneumophila to cause pneumonia is determined by its capability to evade the immune system and grow within human monocytes and their derived macrophages. Human monocytes efficiently...
10.
Abdelaziz D, Amr K, Amer A
Int J Biochem Cell Biol . 2010 Jan; 42(6):789-91. PMID: 20067841
Nlrc4 is a member of the Nod-like receptors (NLRs), a family of cytosolic receptors involved in sensing bacterial molecules. NLRs are a group of proteins containing spans of leucine-rich repeats...