Dale O Kiesewetter
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Explore the profile of Dale O Kiesewetter including associated specialties, affiliations and a list of published articles.
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124
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2888
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Recent Articles
1.
Fernandes B, Olkowski C, Ghaemi B, Basuli F, Shi J, Kiesewetter D, et al.
J Control Release
. 2025 Jan;
379:478-488.
PMID: 39814321
B7-H3, an immunomodulatory protein overexpressed in many cancers, is associated with tumor aggressiveness and poor prognosis, making it a crucial target for imaging to elucidate its role in cancer progression...
2.
Wang Z, Ma W, Yang Z, Kiesewetter D, Wu Y, Lang L, et al.
J Am Chem Soc
. 2024 Oct;
146(42):28973-28984.
PMID: 39383053
Activation of the innate immune Stimulator of Interferon Genes (STING) pathway potentiates antitumor immunity. However, delivering STING agonists systemically to tumors presents a formidable challenge, and resistance to STING monotherapy...
3.
Khan R, Ahn Y, Marriner G, Via L, DHooge F, Lee S, et al.
Nat Commun
. 2024 Jun;
15(1):5239.
PMID: 38937448
Tuberculosis remains a large global disease burden for which treatment regimens are protracted and monitoring of disease activity difficult. Existing detection methods rely almost exclusively on bacterial culture from sputum...
4.
Khan R, Ahn Y, Marriner G, Via L, DHooge F, Lee S, et al.
bioRxiv
. 2023 Jun;
PMID: 37333343
Tuberculosis remains a large global disease burden for which treatment regimens are protracted and monitoring of disease activity difficult. Existing detection methods rely almost exclusively on bacterial culture from sputum...
5.
Tian R, Zeng Q, Zhu S, Lau J, Chandra S, Ertsey R, et al.
Sci Adv
. 2019 Sep;
5(9):eaaw0672.
PMID: 31548981
NIR-II fluorescence imaging greatly reduces scattering coefficients for nearly all tissue types at long wavelengths, benefiting deep tissue imaging. However, most of the NIR-II fluorophores suffer from low quantum yields...
6.
Jacobson O, Wang Z, Yu G, Ma Y, Chen X, Kiesewetter D
Bioorg Med Chem
. 2019 Aug;
27(19):115041.
PMID: 31402203
The efficient radiosynthesis of biomolecules utilizing minute quantities of maleimide substrate is important for availability of novel peptide molecular imaging agents. We evaluated both 3-F-fluoropropane-1-thiol and 2-(2-(2-(2-F-fluoroethoxy)ethoxy)ethoxy)ethane-1-thiol (F-fluoro-PEG thiol) as...
7.
Shan L, Fan W, Wang W, Tang W, Yang Z, Wang Z, et al.
ACS Nano
. 2019 Aug;
13(8):8903-8916.
PMID: 31374171
A major concern about glucose oxidase (GOx)-mediated cancer starvation therapy is its ability to induce serious oxidative damage to normal tissues through the massive production of HO byproducts in the...
8.
Liu Y, Gong C, Dai Y, Yang Z, Yu G, Liu Y, et al.
Biomaterials
. 2019 Jul;
218:119365.
PMID: 31344642
Metal-organic framework (MOF) nanoparticles have shown great potential as carrier platforms in theranostic applications. However, their poor physiological stability in phosphate-based media has limited their biological applications. Here, we studied...
9.
Tang L, Yu F, Tang B, Yang Z, Fan W, Zhang M, et al.
ACS Appl Mater Interfaces
. 2019 Jul;
11(31):27558-27567.
PMID: 31317730
Glutathione (GSH), one of the most significant reducing species in vivo, plays important roles in a variety of diseases and cellular functions. Precise quantification of GSH via advanced noninvasive photoacoustic...
10.
Zhang M, Jacobson O, Kiesewetter D, Ma Y, Wang Z, Lang L, et al.
Bioconjug Chem
. 2019 Jun;
30(6):1745-1753.
PMID: 31181890
As highly expressed in insulinomas, the glucagon-like peptide-1 receptor (GLP-1R) is believed to be an attractive target for diagnosis, localization, and treatment with radiolabeled exendin 4. However, the high and...