Dale E A Lewis
Overview
Explore the profile of Dale E A Lewis including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
315
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Lewis D, Adhya S
EcoSal Plus
. 2024 Dec;
12(1):eesp00142023.
PMID: 39665539
Bacteriophage λ is a paradigm in the field of gene regulation and one of the best-understood systems in genetic regulatory biology. A so-called Genetic Switch determines the mechanisms by which...
2.
Lee S, Lewis D, Adhya S
J Mol Biol
. 2017 Nov;
430(1):58-68.
PMID: 29158090
Bacteriophage λ of Escherichia coli has two alternative life cycles after infection-host survival with lysogen formation, or host lysis and phage production. In a lysogen, CI represses the two lytic...
3.
Qian Z, Trostel A, Lewis D, Lee S, He X, Stringer A, et al.
Front Mol Biosci
. 2016 Dec;
3:74.
PMID: 27900321
The regulatory protein, GalR, is known for controlling transcription of genes related to D-galactose metabolism in . Here, using a combination of experimental and bioinformatic approaches, we identify novel GalR...
4.
Lewis D, Gussin G, Adhya S
J Mol Biol
. 2016 Sep;
428(22):4438-4456.
PMID: 27670714
One of the best understood systems in genetic regulatory biology is the so-called "genetic switch" that determines the choice the phage-encoded CI repressor binds cooperatively to tripartite operators, O and...
5.
Lewis D, Adhya S
Biomolecules
. 2015 Oct;
5(4):2782-807.
PMID: 26501343
Studying the regulation of transcription of the gal operon that encodes the amphibolic pathway of d-galactose metabolism in Escherichia coli discerned a plethora of principles that operate in prokaryotic gene...
6.
Lewis D, Le P, Adhya S
J Mol Biol
. 2014 Dec;
427(4):792-806.
PMID: 25543084
Sequence alignments of promoters in prokaryotes postulated that the frequency of occurrence of a base pair at a given position of promoter elements reflects its contribution to intrinsic promoter strength....
7.
Csiszovszki Z, Lewis D, Le P, Sneppen K, Semsey S
Nucleic Acids Res
. 2012 Sep;
40(20):10064-72.
PMID: 22941635
The P1 promoter of the galactose operon in Escherichia coli is one of the best studied examples of 'extended -10' promoters. Recognition of the P1 promoter does not require specific...
8.
Mazumder A, Bandyopadhyay S, Dhar A, Lewis D, Deb S, Dey S, et al.
Biophys J
. 2012 Apr;
102(7):1580-9.
PMID: 22500758
Stability and induction of the lysogenic state of bacteriophage λ are balanced by a complex regulatory network. A key feature of this network is the mutually exclusive cooperative binding of...
9.
Wang H, Finzi L, Lewis D, Dunlap D
Curr Pharm Biotechnol
. 2009 Aug;
10(5):494-501.
PMID: 19689317
Large, cooperative assemblies of proteins that wrap and/or loop genomic DNA may "epigenetically" shift configurational equilibria that determine developmental pathways. Such is the case of the lambda bacteriophage which may...
10.
Zurla C, Manzo C, Dunlap D, Lewis D, Adhya S, Finzi L
Nucleic Acids Res
. 2009 Mar;
37(9):2789-95.
PMID: 19276206
Recently, it was proposed that DNA looping by the lambda repressor (CI protein) strengthens repression of lytic genes during lysogeny and simultaneously ensures efficient switching to lysis. To investigate this...