D W Niesel
Overview
Explore the profile of D W Niesel including associated specialties, affiliations and a list of published articles.
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43
Citations
866
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Recent Articles
1.
Fadl A, Sha J, Klimpel G, Olano J, Niesel D, Chopra A
Infect Immun
. 2005 Jan;
73(2):1081-96.
PMID: 15664952
Lipopolysaccharide (LPS) and Braun (murein) lipoprotein (Lpp) are major components of the outer membrane of gram-negative enteric bacteria that function as potent stimulators of inflammatory and immune responses. In a...
2.
Sha J, Fadl A, Klimpel G, Niesel D, Popov V, Chopra A
Infect Immun
. 2004 Jun;
72(7):3987-4003.
PMID: 15213144
Septic shock due to Salmonella and other gram-negative enteric pathogens is a leading cause of death worldwide. The role of lipopolysaccharide in sepsis is well studied; however, the contribution of...
3.
Orihuela C, Mills J, Robb C, Wilson C, WATSON D, Niesel D
Infect Immun
. 2001 Nov;
69(12):7565-71.
PMID: 11705934
Differential display-PCR (DDPCR) was used to identify a Streptococcus pneumoniae gene with enhanced transcription during growth in the murine peritoneal cavity. Northern dot blot analysis and comparative densitometry confirmed a...
4.
5.
Robb C, Orihuela C, Ekkelenkamp M, Niesel D
Gene
. 2001 Feb;
262(1-2):169-77.
PMID: 11179681
Shigella genes expressed during infection likely contribute to adaptation and virulence in the host. Using differential display PCR (DDPCR), a cDNA fragment from Shigella flexneri serotype 5 that showed enhanced...
6.
Orihuela C, Janssen R, Robb C, WATSON D, Niesel D
Infect Immun
. 2000 Sep;
68(10):6082-6.
PMID: 10992528
We have examined the properties of Streptococcus pneumoniae cultured in the murine peritoneal cavity and compared its virulence-associated characteristics to those of cultures grown in vitro. Analysis of mRNA levels...
7.
Zhang H, Lichenstein H, Qureshi N, Niesel D, Crowe S, Peterson J, et al.
J Immunol
. 2000 Feb;
164(5):2674-83.
PMID: 10679108
Neutrophil activation plays an important role in the inflammatory response to Gram-negative bacterial infections. LPS has been shown to be a major mediator of neutrophil activation which is accompanied by...
8.
Chopra A, Huang J, Xu X, Burden K, Niesel D, Rosenbaum M, et al.
Microb Pathog
. 1999 Aug;
27(3):155-71.
PMID: 10455006
In this study, the Salmonella enterotoxin gene (stn) was mutated by marker exchange mutagenesis, and the overall virulence of the organism was evaluated. Salmonella marker exchange mutants evoked significantly less...
9.
Zhang H, Niesel D, Peterson J, Klimpel G
Infect Immun
. 1998 Oct;
66(11):5196-201.
PMID: 9784522
Lipoprotein (LP) is a major component of the outer membrane of bacteria in the family Enterobacteriaceae. LP induces proinflammatory cytokine production in macrophages and lethal shock in LPS-responsive and -nonresponsive...
10.
Zhang H, Peterson J, Niesel D, Klimpel G
J Immunol
. 1997 Nov;
159(10):4868-78.
PMID: 9366412
Septic shock is a major cause of death in the world. Although much is known about the role of LPS in septic shock, little is known about the role of...