D W McCourt
Overview
Explore the profile of D W McCourt including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
1261
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Recent Articles
1.
Dustin M, McCourt D, Kornfeld S
J Immunol
. 1996 Mar;
156(5):1841-7.
PMID: 8596035
Binding of peptides to MHC class II Ag generates ligands for TCR of Th lymphocytes. We have identified a novel class of peptides bound to MHC class II: mannose 6-...
2.
Schorey J, Li Q, McCourt D, Ratliff T, Brown E
Infect Immun
. 1995 Jul;
63(7):2652-7.
PMID: 7790081
Mycobacterium leprae, the causative agent of leprosy, is an obligate intracellular pathogen. M. leprae can infect a variety of cells in vivo, including epithelial cells, muscle cells, and Schwann cells,...
3.
Poindexter N, Naziruddin B, McCourt D, Mohanakumar T
J Immunol
. 1995 Apr;
154(8):3880-7.
PMID: 7535816
The molecular nature of tissue-specific Ags involved in MHC-restricted CTL responses is as yet undefined. To determine the specificity of these peptides, their function, and their possible relationship to allograft...
4.
Kitamoto Y, Yuan X, Wu Q, McCourt D, Sadler J
Proc Natl Acad Sci U S A
. 1994 Aug;
91(16):7588-92.
PMID: 8052624
Enterokinase is a protease of the intestinal brush border that specifically cleaves the acidic propeptide from trypsinogen to yield active trypsin. This cleavage initiates a cascade of proteolytic reactions leading...
5.
Lin C, Lindenbach B, Pragai B, McCourt D, Rice C
J Virol
. 1994 Aug;
68(8):5063-73.
PMID: 7518529
The hepatitis C virus (HCV) H strain polyprotein is cleaved to produce at least nine distinct products: NH2-C-E1-E2-NS2-NS3-NS4A-NS4B-NS5A-NS5B-CO OH. In this report, a series of C-terminal truncations and fusion with...
6.
Amberg S, Nestorowicz A, McCourt D, Rice C
J Virol
. 1994 Jun;
68(6):3794-802.
PMID: 8189517
Several of the cleavages required to generate the mature nonstructural proteins from the flaviviral polyprotein are known to be mediated by a complex consisting of NS2B and a serine proteinase...
7.
Dong Z, Thoma R, Crimmins D, McCourt D, Tuley E, Sadler J
J Biol Chem
. 1994 Mar;
269(9):6753-8.
PMID: 8120035
The hemostatic functions of human von Willebrand Factor (vWF) depend on the normal assembly of disulfide-linked multimers from approximately 250-kDa subunits. Subunits initially form dimers through disulfide bonds near the...
8.
Grakoui A, McCourt D, Wychowski C, Feinstone S, Rice C
Proc Natl Acad Sci U S A
. 1993 Nov;
90(22):10583-7.
PMID: 8248148
Host and viral proteinases are believed to be required for the production of at least nine hepatitis C virus (HCV)-specific polyprotein cleavage products. Although several cleavages appear to be catalyzed...
9.
Grakoui A, McCourt D, Wychowski C, Feinstone S, Rice C
J Virol
. 1993 May;
67(5):2832-43.
PMID: 8386278
Processing of the hepatitis C virus (HCV) H strain polyprotein yields at least nine distinct cleavage products: NH2-C-E1-E2-NS2-NS3-NS4A-NS4B-NS5A-NS5B-CO OH. As described in this report, site-directed mutagenesis and transient expression analyses...
10.
Blair H, Teitelbaum S, Grosso L, Lacey D, Tan H, McCourt D, et al.
Biochem J
. 1993 Mar;
290 ( Pt 3):873-84.
PMID: 8457215
Osteoclasts degrade bone matrix, which is mainly type I collagen and hydroxyapatite, in an acidic extracellular compartment. Thus we reasoned that osteoclasts must produce an acid collagenase. We purified this...