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D W Crook

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Articles 79
Citations 1859
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Recent Articles
1.
Stoesser N, George R, Aiken Z, Phan H, Lipworth S, Quan T, et al.
JAC Antimicrob Resist . 2024 Sep; 6(5):dlae140. PMID: 39234218
Background: Healthcare-associated wastewater and asymptomatic patient reservoirs colonized by carbapenemase-producing Enterobacterales (CPE) contribute to nosocomial CPE dissemination, but the characteristics and dynamics of this remain unclear. Methods: We systematically sampled...
2.
Huong D, Walker T, Ha D, Ngoc K, Trung V, Nam L, et al.
IJTLD Open . 2024 Jul; 1(7):320-322. PMID: 39035433
No abstract available.
3.
Chau K, Goodall T, Bowes M, Easterbrook K, Brett H, Hughes J, et al.
Microb Genom . 2023 May; 9(5). PMID: 37145848
Wastewater-based epidemiology (WBE) for population-level surveillance of antimicrobial resistance (AMR) is gaining significant traction, but the impact of wastewater sampling methods on results is unclear. In this study, we characterized...
4.
Chau K, Barker L, Budgell E, Vihta K, Sims N, Kasprzyk-Hordern B, et al.
Environ Int . 2022 Mar; 162:107171. PMID: 35290866
Objectives: We systematically reviewed studies using wastewater for AMR surveillance in human populations, to determine: (i) evidence of concordance between wastewater-human AMR prevalence estimates, and (ii) methodological approaches which optimised...
5.
Kizny Gordon A, Phan H, Lipworth S, Cheong E, Gottlieb T, George S, et al.
J Antimicrob Chemother . 2020 Jan; 75(4):873-882. PMID: 31960024
Background: Hospital outbreaks of carbapenemase-producing organisms, such as blaIMP-4-containing organisms, are an increasing threat to patient safety. Objectives: To investigate the genomic dynamics of a 10 year (2006-15) outbreak of...
6.
Mathers A, Vegesana K, German-Mesner I, Ainsworth J, Pannone A, Crook D, et al.
J Hosp Infect . 2020 Jan; 104(4):456-468. PMID: 31931046
Introduction: Risk factors for carbapenemase-producing Enterobacterales (CPE) acquisition/infection and associated clinical outcomes have been evaluated in the context of clonal, species-specific outbreaks. Equivalent analyses for complex, multi-species outbreaks, which are...
7.
Rooney C, Sheppard A, Clark E, Davies K, Hubbard A, Sebra R, et al.
J Antimicrob Chemother . 2019 Apr; 74(7):1876-1883. PMID: 30989197
Background: Carbapenemase-producing Enterobacteriaceae (CPE) pose a major global health risk. Mobile genetic elements account for much of the increasing CPE burden. Objectives: To investigate CPE colonization and the impact of...
8.
van Aartsen J, Moore C, Parry C, Turner P, Phot N, Mao S, et al.
BMC Microbiol . 2019 Mar; 19(1):59. PMID: 30866820
Background: Extended-spectrum cephalosporin resistance (ESC-R) in Escherichia coli and Klebsiella pneumoniae is a healthcare threat; high gastrointestinal carriage rates are reported from South-east Asia. Colonisation prevalence data in Cambodia are...
9.
Reynolds M, Phan H, George S, Hubbard A, Stoesser N, Maciuca I, et al.
J Antimicrob Chemother . 2019 Feb; 74(5):1207-1211. PMID: 30753576
Background/objectives: Carbapenemase-producing Enterobacteriaceae (CPE) are a public health threat, and have been found in humans, animals and the environment. Carbapenems are not authorized for use in EU or UK companion...
10.
Decraene V, Phan H, George R, Wyllie D, Akinremi O, Aiken Z, et al.
Antimicrob Agents Chemother . 2018 Sep; 62(12). PMID: 30249685
Carbapenem-resistant (CRE) represent a health threat, but effective control interventions remain unclear. Hospital wastewater sites are increasingly being highlighted as important potential reservoirs. We investigated a large carbapenemase (KPC)-producing outbreak...