D W Beno
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Explore the profile of D W Beno including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
243
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Recent Articles
11.
Chen A, Beno D, Davis B
J Biol Chem
. 1996 Oct;
271(42):25994-8.
PMID: 8824237
The regulation of collagen gene expression was studied in culture-activated rat hepatic stellate cells, the fibrogenic effector cell involved in hepatic fibrogenesis. Treatment of cells with a 5-lipoxygenase-specific inhibitor caused...
12.
Brady L, Beno D, Davis B
Biochem J
. 1996 Jun;
316 ( Pt 3):765-9.
PMID: 8670150
Hepatic stellate cells are exposed to elevated bile acid levels during hepatic injury and fibrogenesis. Upon activation, the stellate cell becomes a major effector cell during the development of hepatic...
13.
Davis B, Chen A, Beno D
J Biol Chem
. 1996 May;
271(19):11039-42.
PMID: 8626642
Hepatic stellate cells become activated into myofibroblast-like cells during the early stages of hepatic injury associated with fibrogenesis. The subsequent dysregulation of hepatic stellate cell collagen gene expression is a...
14.
Beno D, Stover A, Mathews H
J Immunol
. 1995 May;
154(10):5273-81.
PMID: 7730631
We have shown previously that IL-2-activated splenocytes can inhibit the growth of Candida albicans hyphae in vitro. Herein we demonstrate that plastic nonadherent lymphocytes that are CD8+ mediate the antifungal...
15.
Beno D, Mullen J, Davis B
Am J Physiol
. 1995 Mar;
268(3 Pt 1):C604-10.
PMID: 7900768
Hepatic Ito cells proliferate during liver injury and fibrogenesis. Platelet-derived growth factor (PDGF)-induced [3H]thymidine incorporation was studied as Ito cells express the PDGF receptor after injury and activation. Pretreatment with...
16.
Beno D, Brady L, Bissonnette M, Davis B
J Biol Chem
. 1995 Feb;
270(8):3642-7.
PMID: 7876102
Recent studies have demonstrated that 1,25-dihydroxyvitamin D3 (D3) can activate Raf kinase and induce Egr expression in cultured rat hepatic Ito cells (Lissoos, T. W., Beno, D. W. A., and...
17.
Beno D, Rapp U, Davis B
Biochim Biophys Acta
. 1994 Jun;
1222(2):292-300.
PMID: 8031866
Ito cell mitogenesis occurs during liver injury and fibrogenesis in vivo coincident with the de novo expression of Ito cell PDGF beta receptor messenger RNA. PDGF-induced mitogenesis was studied in...
18.
Lissoos T, Beno D, Davis B
J Biol Chem
. 1993 Nov;
268(33):25132-8.
PMID: 8227076
1,25-Dihydroxyvitamin D3's (D3) potential mitogenic mechanism of action was pursued in cultured rat hepatic Ito cells, a fibrogenic effector cell which proliferates in vivo during liver injury and fibrogenesis. D3...
19.
Beno D, Awad J, Davis B
Am J Physiol
. 1993 Nov;
265(5 Pt 1):C1388-95.
PMID: 7694498
Ito cell mitogenesis occurs during liver injury and fibrogenesis in vivo. Platelet-derived-growth factor (PDGF)-induced mitogenesis was studied in cultured rat hepatic Ito cells, which resemble the myofibroblast associated with liver...
20.
Davis B, Coll D, Beno D
Biochem J
. 1993 Sep;
294 ( Pt 3):785-91.
PMID: 8379934
Activated Ito-cell-like myofibroblasts proliferate in vivo during human liver injury and subsequent fibrogenesis. To examine the associated regulatory mechanisms, human liver myofibroblasts were characterized after culture purification from mixed liver-cell...