D V Grafham
Overview
Explore the profile of D V Grafham including associated specialties, affiliations and a list of published articles.
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7
Citations
604
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Recent Articles
1.
Chain P, Grafham D, Fulton R, Fitzgerald M, Hostetler J, Muzny D, et al.
Science
. 2009 Oct;
326(5950):236-7.
PMID: 19815760
No abstract available.
2.
Gregory S, Barlow K, McLay K, Kaul R, Swarbreck D, Dunham A, et al.
Nature
. 2006 May;
441(7091):315-21.
PMID: 16710414
The reference sequence for each human chromosome provides the framework for understanding genome function, variation and evolution. Here we report the finished sequence and biological annotation of human chromosome 1....
3.
Deloukas P, Earthrowl M, Grafham D, Rubenfield M, French L, Steward C, et al.
Nature
. 2004 May;
429(6990):375-81.
PMID: 15164054
The finished sequence of human chromosome 10 comprises a total of 131,666,441 base pairs. It represents 99.4% of the euchromatic DNA and includes one megabase of heterochromatic sequence within the...
4.
Humphray S, Oliver K, HUNT A, Plumb R, Loveland J, Howe K, et al.
Nature
. 2004 May;
429(6990):369-74.
PMID: 15164053
Chromosome 9 is highly structurally polymorphic. It contains the largest autosomal block of heterochromatin, which is heteromorphic in 6-8% of humans, whereas pericentric inversions occur in more than 1% of...
5.
Dunham A, MATTHEWS L, Burton J, Ashurst J, Howe K, Ashcroft K, et al.
Nature
. 2004 Apr;
428(6982):522-8.
PMID: 15057823
Chromosome 13 is the largest acrocentric human chromosome. It carries genes involved in cancer including the breast cancer type 2 (BRCA2) and retinoblastoma (RB1) genes, is frequently rearranged in B-cell...
6.
Mungall A, Palmer S, Sims S, Edwards C, Ashurst J, Wilming L, et al.
Nature
. 2003 Oct;
425(6960):805-11.
PMID: 14574404
Chromosome 6 is a metacentric chromosome that constitutes about 6% of the human genome. The finished sequence comprises 166,880,988 base pairs, representing the largest chromosome sequenced so far. The entire...
7.
Deloukas P, MATTHEWS L, Ashurst J, Burton J, GILBERT J, Jones M, et al.
Nature
. 2002 Jan;
414(6866):865-71.
PMID: 11780052
The finished sequence of human chromosome 20 comprises 59,187,298 base pairs (bp) and represents 99.4% of the euchromatic DNA. A single contig of 26 megabases (Mb) spans the entire short...