D Steverding
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Explore the profile of D Steverding including associated specialties, affiliations and a list of published articles.
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39
Citations
698
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Recent Articles
11.
Steverding D
Parasitol Int
. 2001 Mar;
48(3):191-8.
PMID: 11227758
Bloodstream forms of Trypanosoma brucei, the causative agent of sleeping sickness in humans, require transferrin for growth. Uptake of host transferrin is mediated by a heterodimeric glycosylphosphatidylinositol-anchored receptor. The trypanosomal...
12.
Mikus J, Harkenthal M, Steverding D, Reichling J
Planta Med
. 2000 Jun;
66(4):366-8.
PMID: 10865458
The effect of different essential oils as well as of isolated mono- and sesquiterpenes on the viability of bloodstream forms of Trypanosoma brucei, promastigotes of Leishmania major and human HL-60...
13.
Kabiri M, Steverding D
Eur J Biochem
. 2000 May;
267(11):3309-14.
PMID: 10824117
Uptake of host transferrin in bloodstream forms of Trypanosoma brucei is mediated by a heterodimeric, glycosylphosphatidylinositol-anchored receptor. After endocytosis, transferrin is delivered to lysosomes where it is proteolytically degraded. Whether...
14.
Ribonucleotide reductase is regulated via the R2 subunit during the life cycle of Trypanosoma brucei
Breidbach T, Krauth-Siegel R, Steverding D
FEBS Lett
. 2000 May;
473(2):212-6.
PMID: 10812077
We have examined the occurrence of the R1 and R2 subunits of ribonucleotide reductase during the life cycle of Trypanosoma brucei. Whereas the R1 protein is present throughout the life...
15.
Reckenfelderbaumer N, LUDEMANN H, Schmidt H, Steverding D, Krauth-Siegel R
J Biol Chem
. 2000 Mar;
275(11):7547-52.
PMID: 10713060
Trypanosomes and Leishmania, the causative agents of several tropical diseases, lack the glutathione/glutathione reductase system but have trypanothione/trypanothione reductase instead. The uniqueness of this thiol metabolism and the failure to...
16.
Kabiri M, Franco J, Simarro P, Ruiz J, Sarsa M, Steverding D
Trop Med Int Health
. 1999 Dec;
4(10):658-61.
PMID: 10583899
We have developed a sensitive and specific method to identify Trypanosoma brucei ssp. using PCR to amplify conserved expression-site-associated gene 6 and 7 DNA target sequences. Amplification of 10% of...
17.
Fast B, Kremp K, Boshart M, Steverding D
Biochem J
. 1999 Sep;
342 Pt 3:691-6.
PMID: 10477281
Transferrin is an essential growth factor for African trypanosomes. Here we show that expression of the trypanosomal transferrin receptor, which bears no structural similarity with mammalian transferrin receptors, is regulated...
18.
Ansorge I, Steverding D, Melville S, Hartmann C, Clayton C
Mol Biochem Parasitol
. 1999 Jul;
101(1-2):81-94.
PMID: 10413045
African trypanosomes express a heterodimeric transferrin receptor that mediates iron uptake from the host bloodstream. The genes encoding the receptor, ESAG6 and ESAG7, are found at the beginning of VSG...
19.
Scory S, Caffrey C, Stierhof Y, Ruppel A, Steverding D
Exp Parasitol
. 1999 Mar;
91(4):327-33.
PMID: 10092476
Cysteine proteinases were tested for their suitability as targets for chemotherapy of sleeping sickness using the peptidyl inhibitor Z-Phe-Ala-diazomethyl ketone (Z-Phe-Ala-CHN2). In vitro, the inhibitory concentration of Z-Phe-Ala-CHN;2 required to...
20.