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D Steverding

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Articles 39
Citations 698
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Recent Articles
1.
Steverding D
Parasitol Res . 2005 Nov; 98(2):157-61. PMID: 16308729
Bloodstream forms of Trypanosoma brucei contain plasma-membrane-integral acidic ectophosphatase. Here, it is shown by N-terminal sequencing that the ectophosphatase found in ricin-binding material was modified by ubiquitin. Three different ubiquitinated...
2.
Fischer A, Simarro P, Franco J, Becher H, Steverding D
Trop Med Int Health . 2001 Dec; 6(12):1070-4. PMID: 11737844
We tested sera from patients previously treated for human African trypanosomiasis, from patients infected with trypanosomes, and from individuals never diagnosed with African trypanosomiasis living in the Trypanosoma brucei gambiense...
3.
Caffrey C, Hansell E, Lucas K, Brinen L, Alvarez Hernandez A, Cheng J, et al.
Mol Biochem Parasitol . 2001 Nov; 118(1):61-73. PMID: 11704274
Cysteine protease activity of African trypanosome parasites is a target for new chemotherapy using synthetic protease inhibitors. To support this effort and further characterize the enzyme, we expressed and purified...
4.
Kabiri M, Steverding D
Biochem J . 2001 Nov; 360(Pt 1):173-7. PMID: 11696005
An iron superoxide dismutase (FeSOD) gene of the protozoan parasite Trypanosoma brucei has been cloned and its gene product functionally characterized. The gene encodes a protein of 198 residues which...
5.
Kabiri M, Steverding D
J Parasitol . 2001 Nov; 87(5):1189-91. PMID: 11695395
In Trypanosoma brucei, uptake of host transferrin is mediated by a heterodimeric, glycosylphosphatidylinositol-anchored receptor derived from the 2 expression site-associated genes 6 and 7 (ESAG6 and ESAG7). By using specific...
6.
Liu L, Hausladen A, Zeng M, Que L, Heitman J, Stamler J, et al.
Redox Rep . 2001 Oct; 6(4):209-10. PMID: 11642709
No abstract available.
7.
Merschjohann K, Sporer F, Steverding D, Wink M
Planta Med . 2001 Oct; 67(7):623-7. PMID: 11582539
The effect of 34 alkaloids of the piperidine, pyridine, tropane, isoquinoline, indole, quinolizidine, quinoline, purine, and steroidal types on the growth of Trypanosoma brucei, T. congolense, and human HL-60 cells...
8.
Caffrey C, Scory S, Steverding D
Curr Drug Targets . 2001 Jul; 1(2):155-62. PMID: 11465068
The protozoan parasites, Trypanosoma brucei and T. cruzi, that cause sleeping sickness in sub-Saharan Africa and Chagas' Disease in Latin America, respectively, exert significant morbidity and mortality in man. Combinations...
9.
Hofer A, Steverding D, Chabes A, Brun R, Thelander L
Proc Natl Acad Sci U S A . 2001 May; 98(11):6412-6. PMID: 11353848
The drugs in clinical use against African sleeping sickness are toxic, costly, or inefficient. We show that Trypanosoma brucei, which causes this disease, has very low levels of CTP, which...
10.
Mikus J, Steverding D
Parasitol Int . 2001 Mar; 48(3):265-9. PMID: 11227767
A quantitative colorimetric assay using the oxidation-reduction indicator Alamar Blue was developed to measure cytotoxicity of compounds against the protozoan parasite Leishmania. Absorbance increased linearly with the plating density of...