D Skuk
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Explore the profile of D Skuk including associated specialties, affiliations and a list of published articles.
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12
Citations
144
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Recent Articles
1.
El Fahime E, Bouchentouf M, Benabdallah B, Skuk D, Lafreniere J, Chang Y, et al.
Biochem Cell Biol
. 2003 Jul;
81(2):81-90.
PMID: 12870872
Myoblast transplantation (MT) is a potential therapeutic approach for several muscular dystrophies. A major limiting factor is that only a low percentage of the transplanted myoblasts survives the procedure. Recent...
2.
Moisset P, Bonham L, Skuk D, Koeberl D, Brussee V, Goulet M, et al.
Hum Gene Ther
. 2000 Jul;
11(9):1277-88.
PMID: 10890738
Clinical use of human granulocyte-colony stimulating factor (hG-CSF) to treat various diseases involving neutropenia has been previously shown to (1) successfully increase circulating neutrophils, (2) reduce condition-related infections, and (3)...
3.
Skuk D, Goulet M, Roy B, Tremblay J
J Neuropathol Exp Neurol
. 2000 Apr;
59(3):197-206.
PMID: 10744058
The goal of the present study was to determine the feasibility, success, and toxicity of myoblast transplantation (MT) in the whole muscle of primates. Allogenic myoblasts transduced with the beta-galactosidase...
4.
Skuk D, Tremblay J
Microsc Res Tech
. 2000 Feb;
48(3-4):213-22.
PMID: 10679968
Myoblast transplantation (MT) consists of injecting normal or genetically modified myogenic cells into muscles, where they are expected to fuse and form mature fibers. As an experimental approach to treat...
5.
Transplantation of human myoblasts in SCID mice as a potential muscular model for myotonic dystrophy
Skuk D, Furling D, Bouchard J, Goulet M, Roy B, Lacroix Y, et al.
J Neuropathol Exp Neurol
. 1999 Sep;
58(9):921-31.
PMID: 10499435
Myotonic dystrophy (DM), the most frequent hereditary myopathy in adults, is characterized clinically by muscle weakness, myotonia, and systemic symptoms. Although the specific genetic basis for DM has been established,...
6.
Skuk D, Roy B, Goulet M, Tremblay J
Exp Neurol
. 1999 Jan;
155(1):22-30.
PMID: 9918701
Myoblast transplantation (MT) may be a potential treatment for severe recessive hereditary myopathies. The limited results of MT in clinical trials led us to improve this technique in monkeys, an...
7.
Skuk D, Tremblay J
Cell Transplant
. 1998 Oct;
7(5):427-34.
PMID: 9786062
One of the problems limiting myoblast transplantation (MT) is the early death of the transplanted cells. Because complement can be fixed by myoblasts in vitro, and because it has the...
8.
Moisset P, Skuk D, Asselin I, Goulet M, Roy B, Karpati G, et al.
Biochem Biophys Res Commun
. 1998 Jun;
247(1):94-9.
PMID: 9636661
Myoblast transplantation and gene therapy are two promising therapeutical approaches for the treatment of Duchenne Muscular Dystrophy (DMD). So far, both strategies have met many hurdles, mainly because of immune...
9.
Ito H, Vilquin J, Skuk D, Roy B, Goulet M, Lille S, et al.
Neuromuscul Disord
. 1998 Jun;
8(2):95-110.
PMID: 9608563
Dog myoblasts obtained from muscle biopsies were infected in vitro with a defective retroviral vector containing a cytoplasmic beta-galactosidase (beta-Gal) gene. These myoblasts were initially transplanted in the irradiated muscles...
10.
Medici M, Pizzarossa C, Skuk D, Yorio D, Emmanuelli G, Mesa R
Neuromuscul Disord
. 1997 Dec;
7 Suppl 1:S50-2.
PMID: 9392016
Within the last 30 years, sixty-five patients exhibiting the clinical symptoms of oculopharyngeal muscular dystrophy (OPMD) were studied at the Neuromuscular Diseases Unit of the Neurological Institute of Montevideo. They...