D S Finbloom
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Explore the profile of D S Finbloom including associated specialties, affiliations and a list of published articles.
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77
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1742
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Recent Articles
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Donnelly R, Dickensheets H, Finbloom D
J Interferon Cytokine Res
. 1999 Aug;
19(6):563-73.
PMID: 10433356
Interleukin-10 (IL-10) activates a diverse array of functional responses in mononuclear phagocytes. Functional IL-10 receptor (IL-10R) complexes are tetramers consisting of two IL-10R1 polypeptide chains and two IL-10R2 chains. Binding...
3.
Ito S, Ansari P, Sakatsume M, Dickensheets H, Vazquez N, Donnelly R, et al.
Blood
. 1999 Feb;
93(5):1456-63.
PMID: 10029571
Interleukin-10 (IL-10) helps maintain polarized T-helper cells in a T-helper lymphocyte 2 (Th2) phenotype. Part of this process involves the prevention of the development of Th1 cells, which are a...
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Sakatsume M, Stancato L, David M, Silvennoinen O, Saharinen P, Pierce J, et al.
J Biol Chem
. 1998 Feb;
273(5):3021-6.
PMID: 9446616
Signal transduction through the interferongamma (IFNgamma) receptor involves the formation of a ligand-dependent multimolecular association of receptor chains (alpha and beta), Janus tyrosine kinases (Jak1 and Jak2), and the transcription...
6.
Petricoin 3rd E, Ito S, Williams B, Audet S, Stancato L, Gamero A, et al.
Nature
. 1997 Dec;
390(6660):629-32.
PMID: 9403695
Signal transduction through both cytokine and lymphocyte antigen receptors shares some common pathways by which they initiate cellular responses, such as activation of mitogen-activated protein kinase(s). However, other signalling components...
7.
Rosenthal L, Winestock K, Finbloom D
Cell Immunol
. 1997 Dec;
181(2):172-81.
PMID: 9398404
Despite differences in T cell responses induced by interleukin (IL)-2 and IL-7, both cytokines modulate T cell functions by activation of signal transducers and activators of transcription (STAT) proteins. We...
8.
Nakajima H, Liu X, Wynshaw-Boris A, Rosenthal L, Imada K, Finbloom D, et al.
Immunity
. 1997 Dec;
7(5):691-701.
PMID: 9390692
Stat5a was identified as a prolactin-induced transcription factor but also is activated by other cytokines, including interleukin-2 (IL-2) and IL-7. We have now analyzed the immune system of Stat5a-deficient mice....
9.
FELDMAN G, Rosenthal L, Liu X, Hayes M, Wynshaw-Boris A, Leonard W, et al.
Blood
. 1997 Sep;
90(5):1768-76.
PMID: 9292509
Responses of cells to cytokines typically involve the activation of a family of latent DNA binding proteins, referred to as signal transducers and activators of transcription (STAT) proteins, which are...
10.
McCarthy J, Vachhani B, Wahl S, Finbloom D, FELDMAN G
J Immunol
. 1997 Sep;
159(5):2424-30.
PMID: 9278334
Leukocyte integrins are fundamentally important in modulating adhesion to extracellular matrix components and to other cells. This integrin-mediated adhesion controls leukocyte arrest and extravasation during the onset of inflammatory responses....