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D R Micklem

Explore the profile of D R Micklem including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 543
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Recent Articles
1.
McCormack E, Haaland I, Venas G, Forthun R, Huseby S, Gausdal G, et al.
Leukemia . 2011 Nov; 26(5):910-7. PMID: 22064349
Although TP53 mutations are rare in acute myeloid leukemia (AML), wild type p53 function is habitually annulled through overexpression of MDM2 or through various mechanisms including epigenetic silencing by histone...
2.
Micklem D, Adams J, Grunert S, St Johnston D
EMBO J . 2000 Mar; 19(6):1366-77. PMID: 10716936
Drosophila Staufen protein is required for the localization of oskar mRNA to the posterior of the oocyte, the anterior anchoring of bicoid mRNA and the basal localization of prospero mRNA...
3.
Ramos A, Grunert S, Adams J, Micklem D, Proctor M, Freund S, et al.
EMBO J . 2000 Mar; 19(5):997-1009. PMID: 10698941
The double-stranded RNA-binding domain (dsRBD) is a common RNA-binding motif found in many proteins involved in RNA maturation and localization. To determine how this domain recognizes RNA, we have studied...
4.
Schuldt A, Adams J, Davidson C, Micklem D, Haseloff J, St Johnston D, et al.
Genes Dev . 1998 Jun; 12(12):1847-57. PMID: 9637686
Neuroblasts undergo asymmetric stem cell divisions to generate a series of ganglion mother cells (GMCs). During these divisions, the cell fate determinant Prospero is asymmetrically partitioned to the GMC by...
5.
Micklem D, Dasgupta R, Elliott H, Gergely F, Davidson C, Brand A, et al.
Curr Biol . 1997 Jul; 7(7):468-78. PMID: 9210377
Background: Drosophila axis formation requires a series of inductive interactions between the oocyte and the somatic follicle cells. Early in oogenesis, Gurken protein, a member of the transforming growth factor...
6.
Micklem D
Dev Biol . 1995 Dec; 172(2):377-95. PMID: 8612958
Although there are many differences, mRNA localisations in the Xenopus oocyte show some tantalizing similarities to those occurring in Drosophila development. As in Drosophila, transcripts localise to opposite poles of...
7.
Fiering S, Roederer M, Nolan G, Micklem D, Parks D, Herzenberg L
Cytometry . 1991 Jan; 12(4):291-301. PMID: 1905992
The previously reported FACS-Gal assay (Nolan et al., Proc Natl Acad Sci USA 85:2603-2607, 1988) measures E. coli lacZ-encoded beta-galactosidase activity in individual viable eukaryotic cells for a variety of...