D P Bonner
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Explore the profile of D P Bonner including associated specialties, affiliations and a list of published articles.
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63
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808
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Recent Articles
1.
Fung-Tomc J, Gradelski E, Valera L, Huczko E, Bonner D
Int J Antimicrob Agents
. 2002 Jul;
20(1):57-60.
PMID: 12127712
Non-fermentative Gram-negative bacteria (Pseudomonas aeruginosa, Burkholderia cepacia, Stenotrophomonas maltophilia and Acinetobacter spp.) are intrinsically less susceptible to many antimicrobial agents. Two-drug combinations have been used to treat infections caused by...
2.
Fung-Tomc J, Gradelski E, Huczko E, Minassian B, Bonner D
Int J Antimicrob Agents
. 2001 Jul;
18(1):77-80.
PMID: 11463531
Gatifloxacin is an 8-methoxy fluoroquinolone. On quinolones, this side chain imparts increased activity against Gram-positive bacteria and enhanced killing. Gatifloxacin was tested against ofloxacin non-susceptible (ofloxacin MIC>2 mg/l) strains of...
3.
Gradelski E, Kolek B, Bonner D, Valera L, Minassian B, Fung-Tomc J
Int J Antimicrob Agents
. 2001 Feb;
17(2):103-7.
PMID: 11165113
The influence of non-quinolone antimicrobial agents on the antibacterial activities of gatifloxacin and ciprofloxacin was determined using chequerboard, fractional inhibitory concentration, (FIC) and time-kill analysis methods. In the chequerboard method,...
4.
Fung-Tomc J, Minassian B, Kolek B, Huczko E, Aleksunes L, Stickle T, et al.
Antimicrob Agents Chemother
. 2000 Nov;
44(12):3351-6.
PMID: 11083639
The in vitro spectrum of a novel des-fluoro(6) quinolone, BMS-284756, was compared with those of five fluoroquinolones (trovafloxacin, moxifloxacin, levofloxacin, ofloxacin, and ciprofloxacin). BMS-284756 was among the most active and...
5.
Fung-Tomc J, Gradelski E, Valera L, Kolek B, Bonner D
Antimicrob Agents Chemother
. 2000 Apr;
44(5):1377-80.
PMID: 10770784
Killing rates of fluoroquinolones, beta-lactams, and vancomycin were compared against Enterobacteriaceae, Staphylococcus aureus, pneumococci, streptococci, and Enterococcus faecalis. The times required for fluoroquinolones to decrease viability by 3 log(10) were...
6.
Fung-Tomc J, White T, Minassian B, Huczko E, Bonner D
Diagn Microbiol Infect Dis
. 1999 Dec;
35(2):163-7.
PMID: 10579098
The activities of itraconazole and the new triazole BMS-207147 were determined against Candida strains that were susceptible-dose dependent (fluconazole MICs 16 to 32 micrograms/mL) or resistant (MICs > or =...
7.
Fung-Tomc J, Huczko E, Minassian B, Bonner D
Antimicrob Agents Chemother
. 1998 Apr;
42(2):313-8.
PMID: 9527778
The antifungal activity of BMS-207147 (also known as ER-30346) was compared to those of itraconazole and fluconazole against 250 strains of fungi representing 44 fungal species. MICs were determined by...
8.
Fung-Tomc J, Bonner D
Expert Opin Investig Drugs
. 1997 Feb;
6(2):129-45.
PMID: 15989596
Fungal infections are on the rise as the number of patients with compromised immune systems continues to increase. The need for safer and more effective antifungals has resulted in the...
9.
Fung-Tomc J, Gradelski E, Huczko E, Dougherty T, Kessler R, Bonner D
Antimicrob Agents Chemother
. 1996 May;
40(5):1289-93.
PMID: 8723487
The rates of development of resistance to ceftriaxone, ceftazidime, cefepime, and cefpirome in 10 strains of Enterobacter cloacae were determined by daily transfer for 7 days to fresh medium containing...
10.
Fung-Tomc J, Huczko E, Banville J, Menard M, Kolek B, Gradelski E, et al.
Antimicrob Agents Chemother
. 1995 Feb;
39(2):394-9.
PMID: 7726504
A number of carbapenem derivatives were examined to determine the structure-activity relationships required for dependence on porin protein D2 for activity against Pseudomonas aeruginosa. As suggested by J. Trias and...