D J Spergel
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Explore the profile of D J Spergel including associated specialties, affiliations and a list of published articles.
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7
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Recent Articles
1.
Shimshek D, Kim J, Hubner M, Spergel D, Buchholz F, Casanova E, et al.
Genesis
. 2002 Feb;
32(1):19-26.
PMID: 11835670
By applying the mammalian codon usage to Cre recombinase, we improved Cre expression, as determined by immunoblot and functional analysis, in three different mammalian cell lines. The improved Cre (iCre)...
2.
Spergel D, Kruth U, Shimshek D, Sprengel R, Seeburg P
Prog Neurobiol
. 2001 Feb;
63(6):673-86.
PMID: 11165000
This review summarizes recent work on the use of reporter genes to label selected neuronal populations in transgenic mice, with particular emphasis on gonadotropin-releasing hormone (GnRH) neurons. Reporter genes discussed...
3.
Spergel D, Kruth U, Hanley D, Sprengel R, Seeburg P
J Neurosci
. 1999 Mar;
19(6):2037-50.
PMID: 10066257
Mice were generated expressing green fluorescent protein (GFP) under the control of the gonadotropin-releasing hormone (GnRH) promoter. Green fluorescence was observed in, and restricted to, GnRH-immunopositive neuronal somata in the...
4.
Spergel D, Catt K, Rojas E
Neuroendocrinology
. 1996 Feb;
63(2):101-11.
PMID: 9053774
The expression and function of large-conductance Ca2+ -activated K+ (BK) channels in the GT1-7 line of immortalized gonadotropin-releasing hormone (GnRH) neurons was investigated. Ionic currents were recorded using the patch-clamp...
5.
Spergel D, Krsmanovic L, Stojilkovic S, Catt K
Neuroendocrinology
. 1995 May;
61(5):499-508.
PMID: 7617127
To examine the role of calcium signaling in the joint modulation of gonadotropin-releasing hormone (GnRH) secretion by gamma-aminobutyric acid (GABA) and glutamate, cytoplasmic calcium ([Ca2+]i) responses to the two transmitters...
6.
Stojilkovic S, Krsmanovic L, Spergel D, Catt K
Trends Endocrinol Metab
. 1994 Jul;
5(5):201-9.
PMID: 18407209
The pulsatile pattern of gonadotropin-releasing hormone (GnRH) release from the hypothalamus is driven by a functionally interconnected and synchronized network of GnRH neurons termed the GnRH pulse generator. Several recent...
7.
Spergel D, Krsmanovic L, Stojilkovic S, Catt K
Neuroendocrinology
. 1994 Apr;
59(4):309-17.
PMID: 7911229
Glutamate and its receptors are present in the hypothalamus and have been proposed to participate in neuroendocrine regulation, including the control of GnRH secretion. To address the mechanism of glutamate...