P H Seeburg
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Explore the profile of P H Seeburg including associated specialties, affiliations and a list of published articles.
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266
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22481
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Recent Articles
1.
Taylor A, Bus T, Sprengel R, Seeburg P, Rawlins J, Bannerman D
Philos Trans R Soc Lond B Biol Sci
. 2013 Dec;
369(1633):20130149.
PMID: 24298151
The idea that an NMDA receptor (NMDAR)-dependent long-term potentiation-like process in the hippocampus is the neural substrate for associative spatial learning and memory has proved to be extremely popular and...
2.
Smith J, Luenser S, Olson N, Magee E, Olivieri R, Viglia A, et al.
Appl Biochem Biotechnol
. 2013 Nov;
7(6):497-510.
PMID: 24234462
No abstract available.
3.
Grinevich V, Seeburg P, Schwarz M, Jezova D
Endocr Regul
. 2012 Jul;
46(3):153-9.
PMID: 22808907
Homer 1 gene products are involved in the regulation of synaptic transmission and plasticity. Beside other deficits, the Homer 1 knockout (KO) mice show distinct behavioural abnormalities, such as anxiety...
4.
Grinevich V, Jezova D, Gambaryan S, Illarionova A, Kolleker A, Seeburg P, et al.
Horm Metab Res
. 2011 Jul;
43(8):551-6.
PMID: 21773966
Homer 1 gene products are involved in synaptic transmission and plasticity, and hence, distinct behavioral abnormalities, including anxiety- and depression-like behaviors, have been observed in Homer 1 knockout (KO) mice....
5.
Sanderson D, Good M, Seeburg P, Sprengel R, Rawlins J, Bannerman D
Prog Brain Res
. 2008 Apr;
169:159-78.
PMID: 18394473
It is widely believed that synaptic plasticity may provide the neural mechanism that underlies certain kinds of learning and memory in the mammalian brain. The expression of long-term potentiation (LTP)...
6.
Sanderson D, Gray A, Simon A, Taylor A, Deacon R, Seeburg P, et al.
Behav Neurosci
. 2007 Jun;
121(3):559-69.
PMID: 17592947
Genetically modified mice lacking the glutamate receptor A (GluR-A) subunit of the AMPA receptor (GluR-A-/- mice) display normal spatial reference memory but impaired spatial working memory (SWM). This study tested...
7.
Niewoehner B, Single F, Hvalby O, Jensen V, Meyer zum Alten Borgloh S, Seeburg P, et al.
Eur J Neurosci
. 2007 Feb;
25(3):837-46.
PMID: 17313573
Novel spatially restricted genetic manipulations can be used to assess contributions made by synaptic plasticity to learning and memory, not just selectively within the hippocampus, but even within specific hippocampal...
8.
Jaubert P, Golub M, Lo Y, Germann S, Dehoff M, Worley P, et al.
Genes Brain Behav
. 2006 Jun;
6(2):141-54.
PMID: 16734773
Proteins of the Homer1 immediate early gene family have been associated with synaptogenesis and synaptic plasticity suggesting broad behavioral consequences of loss of function. This study examined the behavior of...
9.
GluR-A-dependent synaptic plasticity is required for the temporal encoding of nonspatial information
Reisel D, Bannerman D, Deacon R, Sprengel R, Seeburg P, Rawlins J
Behav Neurosci
. 2005 Nov;
119(5):1298-306.
PMID: 16300436
Four related experiments studied operant performance of mice on differential reinforcement of low rates of responding (DRL) paradigms. Experiment 1 showed that excitotoxic hippocampal lesions impaired performance of a 10-s...
10.
Szumlinski K, Lominac K, Kleschen M, Oleson E, Dehoff M, Schwarz M, et al.
Genes Brain Behav
. 2005 Jul;
4(5):273-88.
PMID: 16011574
Homer proteins are involved in the functional assembly of postsynaptic density proteins at glutamatergic synapses and are implicated in learning, memory and drug addiction. Here, we report that Homer1-knockout (Homer1-KO)...