D J Lew
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Explore the profile of D J Lew including associated specialties, affiliations and a list of published articles.
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41
Citations
3273
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Recent Articles
1.
Gladfelter A, Pringle J, Lew D
Curr Opin Microbiol
. 2001 Dec;
4(6):681-9.
PMID: 11731320
A specialized cortical domain is organized by the septins at the necks of budding yeast cells. Recent findings suggest that this domain serves as a diffusion barrier and also as...
2.
Adamo J, Moskow J, Gladfelter A, Viterbo D, Lew D, Brennwald P
J Cell Biol
. 2001 Nov;
155(4):581-92.
PMID: 11706050
The Rho family GTPase Cdc42 is a key regulator of cell polarity and cytoskeletal organization in eukaryotic cells. In yeast, the role of Cdc42 in polarization of cell growth includes...
3.
Gladfelter A, Moskow J, Zyla T, Lew D
Mol Biol Cell
. 2001 May;
12(5):1239-55.
PMID: 11359919
The highly conserved small GTPase Cdc42p is a key regulator of cell polarity and cytoskeletal organization in eukaryotic cells. Multiple effectors of Cdc42p have been identified, although it is unclear...
4.
Harrison J, Bardes E, Ohya Y, Lew D
Nat Cell Biol
. 2001 Apr;
3(4):417-20.
PMID: 11283616
In many cells the timing of entry into mitosis is controlled by the balance between the activity of inhibitory Wee1-related kinases (Swe1p in budding yeast) and the opposing effect of...
5.
Bose I, Irazoqui J, Moskow J, Bardes E, Zyla T, Lew D
J Biol Chem
. 2000 Dec;
276(10):7176-86.
PMID: 11113154
In budding yeast cells, the cytoskeletal polarization and depolarization events that shape the bud are triggered at specific times during the cell cycle by the cyclin-dependent kinase Cdc28p. Polarity establishment...
6.
Yeh E, Yang C, Chin E, Maddox P, Salmon E, Lew D, et al.
Mol Biol Cell
. 2000 Nov;
11(11):3949-61.
PMID: 11071919
In the budding yeast Saccharomyces cerevisiae, movement of the mitotic spindle to a predetermined cleavage plane at the bud neck is essential for partitioning chromosomes into the mother and daughter...
7.
Moskow J, Gladfelter A, Lamson R, Pryciak P, Lew D
Mol Cell Biol
. 2000 Sep;
20(20):7559-71.
PMID: 11003652
CDC42 encodes a highly conserved GTPase of the Rho family that is best known for its role in regulating cell polarity and actin organization. In addition, various studies of both...
8.
Longtine M, Theesfeld C, McMillan J, Weaver E, Pringle J, Lew D
Mol Cell Biol
. 2000 May;
20(11):4049-61.
PMID: 10805747
Saccharomyces cerevisiae septin mutants have pleiotropic defects, which include the formation of abnormally elongated buds. This bud morphology results at least in part from a cell cycle delay imposed by...
9.
Lew D
Curr Opin Genet Dev
. 2000 Feb;
10(1):47-53.
PMID: 10679396
Cytoskeletal organization is crucial for several aspects of cell-cycle progression but cytoskeletal elements are quite sensitive to environmental perturbations. Two novel checkpoint controls monitor the function of the actin and...
10.
Kim J, Chang K, Choi Y, Song Y, Kang S, Yoon T, et al.
J Acquir Immune Defic Syndr
. 2000 Jan;
22(4):409-12.
PMID: 10634207
No abstract available.