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D J Crankshaw

Explore the profile of D J Crankshaw including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 161
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Recent Articles
1.
Crankshaw D, OBrien Y, Crosby D, Morrison J
J Perinatol . 2017 Jan; 37(5):492-497. PMID: 28125101
Objective: There is controversy as to whether maternal body mass index (BMI) influences the contractility of human myometrium in pregnancy. The aim of this study was to examine spontaneous contractile...
2.
Holloway A, Anger D, Crankshaw D, Wu M, Foster W
J Appl Toxicol . 2007 Aug; 28(3):260-70. PMID: 17685393
Atrazine (ATR) is a pesticide used widely throughout North America. Although not directly estrogenic, ATR treatment has been shown to increase aromatase activity in tumor cell lines. Thus, it is...
3.
Crankshaw D, Rangachari P
Mol Cell Biochem . 2003 Nov; 253(1-2):125-30. PMID: 14619962
Isoprostanes are members of a family of prostaglandin isomers that are produced by free radical-catalysed mechanisms. They have become well-recognized indicators of oxidant-induced cell damage in a variety of pathophysiological...
4.
Crankshaw D
J Pharmacol Toxicol Methods . 2001 Nov; 45(2):123-40. PMID: 11687380
No abstract available.
5.
Popat A, Crankshaw D
Eur J Pharmacol . 2001 Apr; 416(1-2):145-52. PMID: 11282124
Cumulative concentration-effect curves for prostaglandin E(2), sulprostone and butaprost were constructed in matched strips of human non-pregnant myometrium from 14 different donors. All samples were obtained from the mid-lateral wall...
6.
Janssen L, Premji M, Netherton S, Catalli A, Cox G, Keshavjee S, et al.
J Pharmacol Exp Ther . 2000 Oct; 295(2):506-11. PMID: 11046082
Isoprostanes are generated nonenzymatically during free radical-mediated lipid peroxidation, and are used clinically and experimentally as markers of oxidative stress. However, their biological effects are poorly understood. We examined the...
7.
Oliveira L, Stallwood N, Crankshaw D
Br J Pharmacol . 2000 Mar; 129(3):509-14. PMID: 10711349
1. Cumulative concentration-effect curves for the selective prostanoid TP receptor agonist U46619 and six isoprostanes were constructed in the human isolated umbilical artery. 2. All compounds except 8-iso-PGF3 alpha produced...
8.
Senchyna M, Crankshaw D
Br J Pharmacol . 1999 Dec; 128(7):1524-8. PMID: 10602332
1. Cumulative concentration-effect curves for the selective prostanoid TP receptor agonist, U46619, were constructed in strips of human non-pregnant myometrium grouped according to tissue excision site (top, lateral wall, lower...
9.
Boersma J, Janzen K, Oliveira L, Crankshaw D
Br J Pharmacol . 1999 Dec; 128(7):1505-12. PMID: 10602330
1. 5-HT and the prostanoid TP receptor agonists, U46619 and I-BOP, constricted the human umbilical artery with pEC50 values of 7.3+/-0. 2, 6.7+/-0.1, and 7.3+/-0.2, respectively. The selective TP receptor...
10.
Hillock C, Crankshaw D
Eur J Pharmacol . 1999 Sep; 378(1):99-108. PMID: 10478569
Prostanoid EP receptor agonists relaxed cloprostenol-stimulated contraction of human non-pregnant myometrium in vitro with pEC50 values of (n = 4): prostaglandin E2, 7.8+/-0.2 > 1-OH prostaglandin E1, 7.2+/-0.3 > misoprostol,...