D J Beecher
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Explore the profile of D J Beecher including associated specialties, affiliations and a list of published articles.
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11
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Recent Articles
1.
Beecher D, Olsen T, Somers E, Wong A
Infect Immun
. 2000 Aug;
68(9):5269-76.
PMID: 10948154
Bacillus cereus causes a highly fulminant endophthalmitis which usually results in blindness. We previously concluded that hemolysin BL (HBL), a tripartite necrotizing pore-forming toxin, is a probable endophthalmitis virulence factor...
2.
Beecher D, Dasgupta B
J Protein Chem
. 1997 Oct;
16(7):701-12.
PMID: 9330228
Botulinum neurotoxin (NT) serotype A is a approximately 150-kDa dichain protein. Posttranslational nicking of the single-chain NT (residues Pro 1-Leu 1295) by the protease(s) endogenous to Clostridium botulinum excises 10...
3.
Beecher D, Wong A
J Biol Chem
. 1997 Jan;
272(1):233-9.
PMID: 8995253
Hemolysin BL (HBL) is a unique membrane-lytic toxin from Bacillus cereus composed of three distinct proteins, designated B, L1, and L2. HBL produces a paradoxical zone phenomenon in gel diffusion...
4.
Beecher D, Schoeni J, Wong A
Infect Immun
. 1995 Nov;
63(11):4423-8.
PMID: 7591080
Bacillus cereus causes exotoxin-mediated diarrheal food poisoning. Hemolysin BL (HBL) is a well-characterized B. cereus toxin composed of three components (B, L1, and L2) that together possess hemolytic, cytotoxic, dermonecrotic,...
5.
Beecher D, Pulido J, Barney N, Wong A
Infect Immun
. 1995 Feb;
63(2):632-9.
PMID: 7822032
Bacillus cereus is a common cause of highly fulminant posttraumatic and metastatic endophthalmitis. Exotoxins or enzymes likely contribute to the severity of the infection, but specific virulence factors have not...
6.
Beecher D, Wong A
Appl Environ Microbiol
. 1994 Dec;
60(12):4614-6.
PMID: 7811099
The usefulness of two commercial immunoassays for the detection of diarrheal enterotoxin of Bacillus cereus is unclear because the identity of the enterotoxin(s) has not been proven and the kits...
7.
Beecher D, Wong A
Appl Environ Microbiol
. 1994 May;
60(5):1646-51.
PMID: 8017944
Bacillus cereus causes distinct exotoxin-mediated diarrheal and emetic food poisoning syndromes and a variety of nongastrointestinal infections. Evidence is accumulating that hemolysin BL is a major B. cereus virulence factor....
8.
Beecher D, Wong A
Infect Immun
. 1994 Mar;
62(3):980-6.
PMID: 8112873
Bacillus cereus causes diarrheal and emetic food poisoning syndromes as well as a variety of mild to severe infections. A dermonecrotic vascular permeability (VP) factor has been implicated as a...
9.
Heinrichs J, Beecher D, Macmillan J, Zilinskas B
J Bacteriol
. 1993 Nov;
175(21):6760-6.
PMID: 7693651
Previous evidence suggests that hemolysin BL, which consists of a binding component, B, and two lytic components, L1 and L2, is the enterotoxin responsible for the diarrheal form of gastroenteritis...
10.
Beecher D, Macmillan J
Infect Immun
. 1991 May;
59(5):1778-84.
PMID: 1902196
Previously we described the partial purification of a novel hemolysin from Bacillus cereus and showed that hemolytic activity required the combined action of at least two components, called B and...