D G Elferink
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Explore the profile of D G Elferink including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
470
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Recent Articles
1.
Snijders A, Elferink D, Geluk A, van Der Zanden A, Vos K, Schreuder G, et al.
J Immunol
. 2001 Apr;
166(8):4987-93.
PMID: 11290778
Predisposition to rheumatoid arthritis (RA) is thought to be associated with HLA-DR1, -DR4, and -DR10. However, many epidemiological observations are better explained by a model in which the DQ alleles...
2.
Vos K, Miltenburg A, van Meijgaarden K, van den Heuvel M, Elferink D, van Galen P, et al.
Rheumatology (Oxford)
. 2001 Jan;
39(12):1326-31.
PMID: 11136874
Objective: To study the specificity of the peripheral blood mononuclear cell (PBMC) response to peptides derived from human cartilage glycoprotein-39 (HC gp-39) in patients with rheumatoid arthritis (RA) and the...
3.
de Jong R, Altare F, Haagen I, Elferink D, Boer T, Van Breda Vriesman P, et al.
Science
. 1998 Jun;
280(5368):1435-8.
PMID: 9603733
Interleukin-12 (IL-12) is a cytokine that promotes cell-mediated immunity to intracellular pathogens by inducing type 1 helper T cell (TH1) responses and interferon-gamma (IFN-gamma) production. IL-12 binds to high-affinity beta1/beta2...
4.
t Hart B, Elferink D, Drijfhout J, Storm G, van Blooijs L, Bontrop R, et al.
FEBS Lett
. 1997 Jun;
409(1):91-5.
PMID: 9199510
Amino acid residues 3-15 of mycobacterial HSP60 define a dominant T-cell epitope for HLA-DR3+ve humans and Mamu-DR3+ve rhesus monkeys. Our results show that Mamu-DR3 molecules on PBMC can be efficiently...
5.
Geluk A, Elferink D, Slierendregt B, van Meijgaarden K, de Vries R, Ottenhoff T, et al.
J Exp Med
. 1993 Apr;
177(4):979-87.
PMID: 8459225
Many major histocompatibility complex (MHC) polymorphisms originate from ancient structures that predate speciation. As a consequence, members of the Mhc-DRB1*03 allelic lineage are not only present in humans but in...
6.
Bontrop R, Elferink D, Otting N, Jonker M, de Vries R
J Exp Med
. 1990 Jul;
172(1):53-9.
PMID: 1694228
The existence of at least three alleles of the HLA-DRB3 gene within the human population is evident. These alleles express DRw52 determinants and react with monoclonal antibody (mAb) 7.3.19.1. The...
7.
Li S, Elferink D, de Vries R
Hum Immunol
. 1990 May;
28(1):11-26.
PMID: 1692823
We have been studying human T-cell clones that suppress anti-mycobacterial T-cell responses but not T-cell responses to an unrelated antigen or mitogen. In the present paper we report our studies...
8.
van Schooten W, Elferink D, van Embden J, Anderson D, de Vries R
Eur J Immunol
. 1989 Nov;
19(11):2075-9.
PMID: 2480902
Studies in experimental animals have demonstrated that the T cell response to immunogenic proteins is limited to one or a few epitopes on such proteins and that the MHC haplotype...
9.
Bontrop R, Tilanus M, Mikulski M, Elferink D, Termijtelen A, de Vries R, et al.
Immunogenetics
. 1988 Jan;
27(1):40-5.
PMID: 3257099
HLA-DR molecules were isolated from HLA-DR3, -5, and -w6 positive homozygous B-cell lines by immunoprecipitation with monoclonal antibodies and analyzed by gel electrophoretic techniques. DNA isolated from the same cell...
10.
Ottenhoff T, Neuteboom S, Elferink D, de Vries R
J Exp Med
. 1986 Dec;
164(6):1923-39.
PMID: 2431092
MHC class II molecules carry the restriction determinants (RDs) for antigen presentation to antigen-specific Th lymphocytes. This restriction of T cell activation endows those molecules with a key role in...