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D Frazer

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Articles 16
Citations 219
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Recent Articles
1.
LeBlanc A, Cumpston J, Chen B, Frazer D, Castranova V, Nurkiewicz T
J Toxicol Environ Health A . 2010 Jan; 72(24):1576-84. PMID: 20077232
Exposure to fine particulate matter (PM, mean aerodynamic diameter <or=2.5 microm) has been shown to be a risk factor for cardiovascular disease mortality and may contribute to acute coronary events...
2.
LeBlanc A, Moseley A, Chen B, Frazer D, Castranova V, Nurkiewicz T
Cardiovasc Toxicol . 2009 Dec; 10(1):27-36. PMID: 20033351
We have shown that nanoparticle inhalation impairs endothelium-dependent vasodilation in coronary arterioles. It is unknown whether local reactive oxygen species (ROS) contribute to this effect. Rats were exposed to TiO(2)...
3.
Dash D, George S, OPrey D, Burns D, Nabili S, Donnelly U, et al.
Eye (Lond) . 2009 Sep; 24(6):1085-92. PMID: 19763142
Purpose: To perform mutational screening of the visual system homeobox gene 1 (VSX1; MIM#605020) in patients with sporadic and familial keratoconus (MIM#148300) in a European population and, for the first...
4.
Zhao H, Yin X, Frazer D, Barger M, Siegel P, Millecchia L, et al.
Mutat Res . 2004 Jan; 557(2):137-49. PMID: 14729368
Asphalt fumes are complex mixtures of aerosols and vapors containing various organic compounds, including polycyclic aromatic hydrocarbons (PAHs). Previously, we have demonstrated that inhalation exposure of rats to asphalt fumes...
5.
Hubbs A, Battelli L, Goldsmith W, Porter D, Frazer D, Friend S, et al.
Toxicol Appl Pharmacol . 2002 Dec; 185(2):128-35. PMID: 12490137
As the result of a high prevalence of fixed airways obstruction in workers at a microwave popcorn manufacturing plant, we examined the hypothesis that vapors of butter flavoring used in...
6.
Schimmel C, Frazer D, Glenny R
Am J Physiol Heart Circ Physiol . 2001 May; 280(6):H2496-506. PMID: 11356604
Seven fluorescent microsphere colors can be used in a single experiment to estimate regional blood flow without correcting for spillover of emitted fluorescence. To extend the method to 13 colors,...
7.
Hubbs A, Minhas N, Jones W, Greskevitch M, Battelli L, Porter D, et al.
Toxicol Sci . 2001 Apr; 61(1):135-43. PMID: 11294984
Inhalation of silica dust is associated with pulmonary fibrosis. Therefore, substitute abrasive materials have been suggested for use in abrasive blasting operations. To date, toxicological evaluation of most substitute abrasives...
8.
Schimmel C, Frazer D, Huckins S, Glenny R
Comput Methods Programs Biomed . 2000 Apr; 62(2):115-25. PMID: 10764938
The fluorescent microsphere (FM) method for determination of regional organ blood flow is labor intensive, requiring processing of 100 s to 1000 s of samples per organ. To save time...
9.
Tsang J, Frazer D, Hlastala M
J Appl Physiol (1985) . 2000 Feb; 88(2):705-12. PMID: 10658041
By using the multiple-breath helium washout technique, ventilation heterogeneity (VH) after embolic injury in the lung can be quantitatively partitioned into the conductive and acinar components. Total VH, represented by...
10.
Lichtenberg P, Smith M, Frazer D, Molinari V, Rosowsky E, Crose R, et al.
Gerontologist . 1998 Mar; 38(1):122-7. PMID: 9499660
Psychologists in Long-Term Care (PLTC), a national network established in 1983, has developed, with input from colleagues and consumers, standards for psychological practice in long-term care facilities. These standards address...