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D F Werner

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Articles 10
Citations 338
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Recent Articles
1.
Santerre-Anderson J, Werner D
Neurochem Res . 2020 Apr; 45(7):1592-1601. PMID: 32274627
Ethanol consumption typically begins during adolescence and is associated with age-dependent responses and maladaptive neuronal consequences. Our previous work established the role of a putative signaling cascade involving cytoplasmic phospholipase...
2.
Przybysz K, Werner D, Diaz M
Neuropharmacology . 2017 Feb; 117:124-133. PMID: 28163104
Anxiety disorders are one of the most common and debilitating mental illnesses worldwide. Growing evidence indicates an age-dependent rise in the incidence of anxiety disorders from adolescence through adulthood, suggestive...
3.
Suryanarayanan A, Carter J, Landin J, Morrow A, Werner D, Spigelman I
Neuropharmacology . 2016 Mar; 107:181-188. PMID: 27016017
Mounting evidence indicates that ethanol (EtOH) exposure activates neuroimmune signaling. Alterations in pro-inflammatory cytokines after acute and chronic EtOH exposure have been heavily investigated. In contrast, little is known about...
4.
Santerre J, Kolitz E, Pal R, Rogow J, Werner D
Neurochem Res . 2015 Mar; 40(5):1023-31. PMID: 25791059
Ethanol consumption typically begins during adolescence, a developmental period which exhibits many age-dependent differences in ethanol behavioral sensitivity. Protein kinase C (PKC) activity is largely implicated in ethanol-behaviors, and our...
5.
Santerre J, Rogow J, Kolitz E, Pal R, Landin J, Gigante E, et al.
Neuroscience . 2014 Sep; 280:50-9. PMID: 25218807
AMPA receptor GluA2 subunits are strongly implicated in cognition, and prior work suggests that these subunits may be regulated by atypical protein kinase C (aPKC) isoforms. The present study assessed...
6.
Blednov Y, Borghese C, McCracken M, Benavidez J, Geil C, Osterndorff-Kahanek E, et al.
J Pharmacol Exp Ther . 2010 Sep; 336(1):145-54. PMID: 20876231
GABA type A receptors (GABA(A)-Rs) are potential targets of ethanol. However, there are multiple subtypes of this receptor, and, thus far, individual subunits have not been definitively linked with specific...
7.
Werner D, Swihart A, Rau V, Jia F, Borghese C, McCracken M, et al.
J Pharmacol Exp Ther . 2010 Sep; 336(1):134-44. PMID: 20807777
The mechanism by which the inhaled anesthetic isoflurane produces amnesia and immobility is not understood. Isoflurane modulates GABA(A) receptors (GABA(A)-Rs) in a manner that makes them plausible targets. We asked...
8.
Chandra D, Jia F, Liang J, Peng Z, Suryanarayanan A, Werner D, et al.
Proc Natl Acad Sci U S A . 2006 Sep; 103(41):15230-5. PMID: 17005728
The neurotransmitter GABA mediates the majority of rapid inhibition in the CNS. Inhibition can occur via the conventional mechanism, the transient activation of subsynaptic GABAA receptors (GABAA-Rs), or via continuous...
9.
Borghese C, Werner D, Topf N, Baron N, Henderson L, Boehm 2nd S, et al.
J Pharmacol Exp Ther . 2006 Jun; 319(1):208-18. PMID: 16807363
Volatile anesthetics and alcohols enhance transmission mediated by gamma-aminobutyric acid type A receptors (GABA(A)Rs) in the central nervous system, an effect that may underlie some of the behavioral actions of...
10.
Werner D
Ind Med Surg . 1965 Sep; 34(9):717-9. PMID: 5213273
No abstract available.