D F Stojdl
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Explore the profile of D F Stojdl including associated specialties, affiliations and a list of published articles.
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16
Citations
867
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Recent Articles
1.
Roy D, Geoffroy K, Marguerie M, Khan S, Martin N, Kmiecik J, et al.
Nat Commun
. 2021 May;
12(1):2626.
PMID: 33976179
By conferring systemic protection and durable benefits, cancer immunotherapies are emerging as long-term solutions for cancer treatment. One such approach that is currently undergoing clinical testing is a therapeutic anti-cancer...
2.
Roy D, Power A, Bourgeois-Daigneault M, Falls T, Ferreira L, Stern A, et al.
J Control Release
. 2015 Oct;
220(Pt A):210-221.
PMID: 26482080
Due to cancer's genetic complexity, significant advances in the treatment of metastatic disease will require sophisticated, multi-pronged therapeutic approaches. Here we demonstrate the utility of a Drosophila melanogaster cell platform...
3.
Courteau L, Crasto J, Hassanzadeh G, Baird S, Hodgins J, Liwak-Muir U, et al.
Cell Death Dis
. 2015 Aug;
6:e1837.
PMID: 26247723
Subcellular localization of RNA-binding proteins is a key determinant of their ability to control RNA metabolism and cellular stress response. Using an RNAi-based kinome-wide screen, we identified hexokinase 2 (HK2)...
4.
Mahoney D, Stojdl D
Br J Cancer
. 2012 Nov;
108(2):245-9.
PMID: 23169279
Functional genomic screening has emerged as a powerful approach for understanding complex biological phenomena. Of the available tools, genome-wide RNA interference (RNAi) technology is unquestionably the most incisive, as it...
5.
Cheung H, St Jean M, Beug S, Lejmi-Mrad R, LaCasse E, Baird S, et al.
Cell Death Dis
. 2011 Apr;
2:e146.
PMID: 21490678
Smac mimetic compounds (SMCs) are experimental small molecules that induce tumour necrosis factor alpha (TNFα)-dependent cancer cell death by targeting the inhibitor of apoptosis proteins. However, many cancer cell lines...
6.
Mahoney D, Stojdl D
Cytokine Growth Factor Rev
. 2010 Mar;
21(2-3):161-7.
PMID: 20207578
Replicating virus-based therapeutics for cancer, or oncolytic virus therapy (OVT), is rapidly emerging as a promising treatment modality for a wide range of cancers. In pre-clinical studies, oncolytic viruses have...
7.
Bell J, Garson K, Lichty B, Stojdl D
Curr Gene Ther
. 2002 Jul;
2(2):243-54.
PMID: 12109220
Despite significant improvements in early detection and refinements of therapeutic protocols over the last several decades, cancer remains one of the leading causes of death in North America. In particular,...
8.
Desforges M, Charron J, Berard S, Beausoleil S, Stojdl D, Despars G, et al.
Virus Res
. 2001 May;
76(1):87-102.
PMID: 11376849
Acute infection of fibroblastic cell lines by the Indiana strain of vesicular stomatitis virus (VSV) usually induces dramatic cytopathic effects and shutoff of cellular gene expression. We have compared a...
9.
Stojdl D, Abraham N, Knowles S, Marius R, Brasey A, Lichty B, et al.
J Virol
. 2000 Sep;
74(20):9580-5.
PMID: 11000229
Interferon (IFN)-induced antiviral responses are mediated through a variety of proteins, including the double-stranded RNA-dependent protein kinase PKR. Here we show that fibroblasts derived from PKR(-/-) mice are more permissive...
10.
Stojdl D, Lichty B, Knowles S, Marius R, Atkins H, Sonenberg N, et al.
Nat Med
. 2000 Jul;
6(7):821-5.
PMID: 10888934
Interferons are circulating factors that bind to cell surface receptors, activating a signaling cascade, ultimately leading to both an antiviral response and an induction of growth inhibitory and/or apoptotic signals...