D Darmer
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Explore the profile of D Darmer including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
257
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Recent Articles
1.
Morawietz H, Rohrbach S, Rueckschloss U, Schellenberger E, Hakim K, Zerkowski H, et al.
Eur J Clin Invest
. 2006 Sep;
36(10):705-12.
PMID: 16968466
Background: The efficacy of angiotensin-converting enzyme (ACE) inhibitors has been demonstrated in large clinical trials, but knowledge of the underlying mechanisms remains incomplete. Therefore, this study investigated the impact of...
2.
Janssen P, Hasenfuss G, Zeitz O, Lehnart S, Prestle J, Darmer D, et al.
Am J Physiol Heart Circ Physiol
. 2001 Dec;
282(1):H349-56.
PMID: 11748081
Increased mechanical load has been proposed as an inductor of apoptosis, but it is unknown whether this can occur in the range of pre- and afterloads that prevail in the...
3.
Vasilets L, Darmer D, Isenberg G, Schwarz W
Pflugers Arch
. 2001 Nov;
443(1):84-91.
PMID: 11692271
To address the question of whether the function of Na+,K+-ATPases differs in the heart of young and old rats, enzymes formed from the alpha1 or alpha2 isoform with the beta1...
4.
Scheubel R, Bartling B, Stein S, Darmer D, Holtz J, Pregla R, et al.
Thorac Cardiovasc Surg
. 2001 Oct;
49(5):268-72.
PMID: 11605135
Hemodynamic unloading using the ventricular assist device [VAD] results in partial functional recovery of failing hearts that show increased susceptibility to cardiomyocyte apoptosis. The caspase cascade is the central element...
5.
Bartling B, Tostlebe H, Darmer D, Holtz J, Silber R, Morawietz H
Biochem Biophys Res Commun
. 2000 Nov;
278(3):740-6.
PMID: 11095978
Laminar shear stress exerts potent anti-apoptotic effects. Therefore, we analyzed the influence of laminar shear stress on the expression of apoptosis-regulating genes in human umbilical vein endothelial cells (HUVEC). Application...
6.
Akcetin Z, Pregla R, Darmer D, Bromme H, Holtz J
Transpl Int
. 2000 Aug;
13(4):297-302.
PMID: 10959483
Ischemia-reperfusion injury is known to induce the inducible form of the 70 kDa heat shock protein HSP70i (or HSP72) mainly via rapid activation of heat shock transcription factor 1 (HSF1)....
7.
Morawietz H, Talanow R, Szibor M, Rueckschloss U, Schubert A, Bartling B, et al.
J Physiol
. 2000 Jun;
525 Pt 3:761-70.
PMID: 10856127
In this study, the effect of shear stress on the expression of genes of the human endothelin-1 system was examined. Primary cultures of human umbilical vein endothelial cells (HUVEC) were...
8.
Schubert A, Cattaruzza M, Hecker M, Darmer D, Holtz J, Morawietz H
Circ Res
. 2000 Jan;
87(12):1188-94.
PMID: 11110777
The flowing blood generates shear stress at the endothelial cell surface. The endothelial cells modify their phenotype by alterations in gene expression in response to different levels of fluid shear...
9.
Bartling B, Milting H, Schumann H, Darmer D, Arusoglu L, Koerner M, et al.
Circulation
. 1999 Nov;
100(19 Suppl):II216-23.
PMID: 10567307
Background: In patients with end-stage heart failure, characterized by an increased susceptibility to cardiomyocyte apoptosis and a labile cardiomyocyte calcium homeostasis, a ventricular assist device (VAD) is implanted for bridging...
10.
Akcetin Z, Pregla R, Darmer D, Heynemann H, Haerting J, Bromme H, et al.
Urol Res
. 1999 Nov;
27(5):306-11.
PMID: 10550516
Ischemia-reperfusion injury in the kidney is known to cause induction of the inducible form of the 70 kDa heat shock protein HSP70i (or HSP72). However, knowledge of the expressional regulation...