D D Shoemaker
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Explore the profile of D D Shoemaker including associated specialties, affiliations and a list of published articles.
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36
Citations
4010
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Recent Articles
11.
Giaever G, Shoemaker D, Jones T, Liang H, Winzeler E, Astromoff A, et al.
Nat Genet
. 1999 Mar;
21(3):278-83.
PMID: 10080179
Lowering the dosage of a single gene from two copies to one copy in diploid yeast results in a heterozygote that is sensitized to any drug that acts on the...
12.
Ross K, Krieger M, Shoemaker D, Vargo E, Keller L
Genetics
. 1997 Oct;
147(2):643-55.
PMID: 9335601
We describe genetic structure at various scales in native populations of the fire ant Solenopsis invicta using two classes of nuclear markers, allozymes and microsatellites, and markers of the mitochondrial...
13.
Shoemaker D, Lashkari D, Morris D, Mittmann M, Davis R
Nat Genet
. 1996 Dec;
14(4):450-6.
PMID: 8944025
A quantitative and highly parallel method for analysing deletion mutants has been developed to aid in determining the biological function of thousands of newly identified open reading frames (ORFs) in...
14.
Hurley T, Ryan M, Shoemaker D
Arch Oral Biol
. 1994 Mar;
39(3):205-12.
PMID: 8018052
To determine its effect on cytosolic Ca2+ levels (Ca2+i) and to assess its role as an autonomic cotransmitter, ATP was added to suspensions of rat pancreatic or submandibular gland acini...
15.
Hurley T, Shoemaker D, Ryan M
Am J Physiol
. 1993 Dec;
265(6 Pt 1):C1472-8.
PMID: 8279511
In dose-dependent fashion, extracellular ATP reduces the increase in cytosolic Ca2+ concentration ([Ca2+]o) due to mobilization of cellular Ca2+ stores by both epinephrine [half-maximal inhibitory concentration (IC50) = 35.7 +/-...
16.
Lundberg K, Shoemaker D, Adams M, Short J, Sorge J, Mathur E
Gene
. 1991 Dec;
108(1):1-6.
PMID: 1761218
A thermostable DNA polymerase which possesses an associated 3'-to-5' exonuclease (proofreading) activity has been isolated from the hyperthermophilic archaebacterium, Pyrococcus furiosus (Pfu). To test its fidelity, we have utilized a...
17.
Reich N, Maegley K, Shoemaker D, Everett E
Biochemistry
. 1991 Mar;
30(11):2940-6.
PMID: 2007130
Native EcoRI DNA methyltransferase (Mtase, Mr 38,050) is proteolyzed by trypsin to generate an intermediate 36-kDa fragment (p36) followed by the formation of two polypeptides of Mr 23,000 and 13,000...
18.
Grem J, Rubinstein L, King S, Cheson B, Hawkins M, Shoemaker D
Invest New Drugs
. 1990 May;
8(2):227-38.
PMID: 2200759
Tiazofurin, an investigational antimetabolite, is undergoing clinical evaluation in leukemia. We analyzed the data base of 198 patients entered in Phase I trials to characterize the incidence and severity of...
19.
Grem J, Ellenberg S, King S, Shoemaker D
J Natl Cancer Inst
. 1988 Oct;
80(16):1313-8.
PMID: 2971817
Trimetrexate, an investigational antifol, has been associated with marked variability in drug tolerance among patients. The agent is extensively protein bound, and hepatic biotransformation plays a major role in its...
20.
Grem J, Shoemaker D, Hoth D, King S, Plowman J, Zaharko D, et al.
Invest New Drugs
. 1987 Dec;
5(4):315-28.
PMID: 2449402
Arabinosyl-5-azacytosine is a new compound which has been selected by the Division of Cancer Treatment, National Cancer Institute for clinical development as an antineoplastic agent based on its high degree...