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D D Newmeyer

Explore the profile of D D Newmeyer including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 3535
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Recent Articles
1.
Kushnareva Y, Seong Y, Andreyev A, Kuwana T, Kiosses W, Votruba M, et al.
Cell Death Dis . 2016 Jul; 7:e2309. PMID: 27468686
Mutations in the opa1 (optic atrophy 1) gene lead to autosomal dominant optic atrophy (ADOA), a hereditary eye disease. This gene encodes the Opa1 protein, a mitochondrial dynamin-related GTPase required...
2.
Volkmann N, Marassi F, Newmeyer D, Hanein D
Cell Death Differ . 2013 Oct; 21(2):206-15. PMID: 24162659
Apoptosis, a mechanism for programmed cell death, has key roles in human health and disease. Many signals for cellular life and death are regulated by the BCL-2 family proteins and...
3.
Yamaguchi R, Andreyev A, Murphy A, Perkins G, Ellisman M, Newmeyer D
Cell Death Differ . 2006 Sep; 14(3):616-24. PMID: 16977331
In apoptosis, Bcl-2-family proteins regulate the barrier function of the mitochondrial outer membrane (MOM), controlling the release of proapoptotic proteins from the intermembrane space into the cytoplasm. This process can...
4.
KASPAR A, Okada S, Kumar J, Poulain F, Drouvalakis K, Kelekar A, et al.
J Immunol . 2001 Jun; 167(1):350-6. PMID: 11418670
Granulysin is an antimicrobial and tumoricidal molecule expressed in granules of CTL and NK cells. In this study, we show that granulysin damages cell membranes based upon negative charge, disrupts...
5.
Waterhouse N, Goldstein J, Kluck R, Newmeyer D, Green D
Methods Cell Biol . 2001 Jun; 66:365-91. PMID: 11396012
No abstract available.
6.
Waterhouse N, Goldstein J, von Ahsen O, Schuler M, Newmeyer D, Green D
J Cell Biol . 2001 Apr; 153(2):319-28. PMID: 11309413
During apoptosis, cytochrome c is released into the cytosol as the outer membrane of mitochondria becomes permeable, and this acts to trigger caspase activation. The consequences of this release for...
7.
Pinkoski M, Waterhouse N, Heibein J, Wolf B, Kuwana T, Goldstein J, et al.
J Biol Chem . 2001 Mar; 276(15):12060-7. PMID: 11278459
Cytotoxic T lymphocytes kill virus-infected and tumor cell targets through the concerted action of proteins contained in cytolytic granules, primarily granzyme B and perforin. Granzyme B, a serine proteinase with...
8.
von Ahsen O, Waterhouse N, Kuwana T, Newmeyer D, Green D
Cell Death Differ . 2001 Feb; 7(12):1192-9. PMID: 11175256
Release of cytochrome c from the mitochondria plays an integral role in apoptosis; however, the mechanism by which cytochrome c is released remains one of the conundrums that has occupied...
9.
von Ahsen O, Renken C, Perkins G, Kluck R, Bossy-Wetzel E, Newmeyer D
J Cell Biol . 2000 Sep; 150(5):1027-36. PMID: 10973993
Proapoptotic members of the Bcl-2 protein family, including Bid and Bax, can activate apoptosis by directly interacting with mitochondria to cause cytochrome c translocation from the intermembrane space into the...
10.
von Ahsen O, Newmeyer D
Methods Enzymol . 2000 Jul; 322:183-98. PMID: 10914015
No abstract available.