D C Waters
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Explore the profile of D C Waters including associated specialties, affiliations and a list of published articles.
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17
Citations
140
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Recent Articles
1.
Hipskind P, Howbert J, Bruns R, Cho S, Crowell T, Foreman M, et al.
J Med Chem
. 1996 Feb;
39(3):736-48.
PMID: 8576917
Early structure-activity studies on racemic tryptophan ester and amide NK-1 antagonists 5-7 led to the discovery that the potency of the series could be markedly increased by moving the carbonyl...
2.
Gitter B, Bruns R, Howbert J, Waters D, Threlkeld P, Cox L, et al.
J Pharmacol Exp Ther
. 1995 Nov;
275(2):737-44.
PMID: 7473161
LY303870 [(R)-1-[N-(2-methoxybenzyl)acetylamino]-3-(1H-indol-3-yl)-2-[N-(2-(4- (piperidin-1-yl)piperidin-1-yl)acetyl)amino]propane] is a new, potent and selective nonpeptide neurokinin-1 (NK-1) receptor antagonist. LY303870 bound selectively and with high affinity to human peripheral (Ki = 0.15 nM) and central...
3.
Gitter B, Waters D, Threlkeld P, Lovelace A, Matsumoto K, Bruns R
Eur J Pharmacol
. 1995 May;
289(3):439-46.
PMID: 7556412
The immunosuppressive cyclic undecapeptide, cyclosporin A, inhibited the binding of [125I]substance P to tachykinin NK1 receptors expressed by human IM-9 lymphoblastoid cells, U-373 MG human astrocytoma cells and guinea pig...
4.
Gitter B, Regoli D, Howbert J, Glasebrook A, Waters D
J Neuroimmunol
. 1994 Apr;
51(1):101-8.
PMID: 7512575
Functional NK-1 (substance P) receptors have been demonstrated previously on astrocytes from primary newborn rat brain cultures and human astrocytoma cells lines by specific [125I]-Bolton Hunter substance P (SP) binding...
5.
May P, Gitter B, Waters D, Simmons L, Becker G, Small J, et al.
Neurobiol Aging
. 1992 Sep;
13(5):605-7.
PMID: 1281290
beta A4 peptide (beta AP) accumulates in amyloid plaques of Alzheimer's disease and may contribute to neuronal degeneration. Conflicting observations have been reported regarding the direct in vitro and in...
6.
Gitter B, Waters D, Bruns R, Mason N, Nixon J, Howbert J
Eur J Pharmacol
. 1991 May;
197(2-3):237-8.
PMID: 1717291
No abstract available.
7.
Rouissi N, Gitter B, Waters D, Howbert J, Nixon J, Regoli D
Biochem Biophys Res Commun
. 1991 Apr;
176(2):894-901.
PMID: 1709018
Two members of a new class of non-peptide antagonists of substance P, (+-)-cis-3-(2-methoxybenzylamino)-2-benzhydrylquinuclidine [(+/-)-CP-96,345; I] and (+-)-cis-3-(2-chlorobenzylamino)-2-benzhydrylquinuclidine [II], were tested for their ability to antagonize neurokinin-induced contractions of the rabbit...
8.
Hjelle J, Golinska B, Waters D, Steidley K, Miller M, McCarroll D, et al.
Perit Dial Int
. 1991 Jan;
11(4):307-16.
PMID: 1721546
A survey of lectin-binding specificities present on rodent and human mesothelial cells propagated and maintained in tissue culture was made using fluorescein isothiocynate conjugated (FITC) lectins. Rodent and human cells...
9.
Hjelle J, Golinska B, Waters D, Steidley K, McCarroll D, Pavlina T, et al.
Perit Dial Int
. 1991 Jan;
11(3):207-12.
PMID: 1655064
The nature of intracytoplasmic lipid inclusions found in cultured rabbit and rat peritoneal mesothelial cells was examined by ultrastructural and biochemical techniques. Transmission electron microscopy also demonstrated extracellular release of...
10.
Hjelle J, Waters D, Golinska B, Steidley K, Burmeister V, Caughey R, et al.
Am J Kidney Dis
. 1990 Feb;
15(2):123-36.
PMID: 2154094
Renal cystic epithelia and peritoneal mesothelia from two humans with autosomal recessive polycystic kidney disease (ARPKD) were grown in culture. Cystic epithelial and mesothelial cells formed continuous monolayers in vitro....