D C Phillips
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Explore the profile of D C Phillips including associated specialties, affiliations and a list of published articles.
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85
Citations
2386
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Recent Articles
1.
Phillips D, Xiao Y, Lam L, Litvinovich E, Roberts-Rapp L, Souers A, et al.
Blood Cancer J
. 2016 Mar;
6:e403.
PMID: 26967820
No abstract available.
2.
Phillips D, Xiao Y, Lam L, Litvinovich E, Roberts-Rapp L, Souers A, et al.
Blood Cancer J
. 2015 Nov;
5:e368.
PMID: 26565405
As a population, non-Hodgkin's lymphoma (NHL) cell lines positive for the t(14;18) translocation and/or possessing elevated BCL2 copy number (CN; BCL2(High)) are exquisitely sensitive to navitoclax or the B-cell lymphoma...
3.
Leverson J, Zhang H, Chen J, Tahir S, Phillips D, Xue J, et al.
Cell Death Dis
. 2015 Jan;
6:e1590.
PMID: 25590800
The anti-apoptotic protein MCL-1 is a key regulator of cancer cell survival and a known resistance factor for small-molecule BCL-2 family inhibitors such as ABT-263 (navitoclax), making it an attractive...
4.
Ackler S, Mitten M, Chen J, Clarin J, Foster K, Jin S, et al.
Br J Pharmacol
. 2012 May;
167(4):881-91.
PMID: 22624727
Background And Purpose: Bendamustine with or without rituximab provides an effective and more tolerable alternative to the polytherapy cyclophosphamide-doxorubicin-vincristine-prednisolone (CHOP) in the treatment of haematological tumours and is currently approved...
5.
Garrison S, Phillips D, Jeffers J, Chipuk J, Parsons M, Rehg J, et al.
Cell Death Differ
. 2011 Oct;
19(4):642-9.
PMID: 22015606
Using genetically modified mouse models, we report here that p53 upregulated modulator of apoptosis (Puma) and Bcl-2 interacting mediator of cell death (Bim), two pro-apoptotic members of the B-cell lymphoma...
6.
Phillips D, Hunt J, Moneypenny C, Maclean K, McKenzie P, Harris L, et al.
Cell Death Differ
. 2007 Jul;
14(10):1780-91.
PMID: 17627285
The sphingoplipid ceramide is responsible for a diverse range of biochemical and cellular responses including a putative role in modulating cell cycle progression. Herein, we describe that an accumulation of...
7.
A caspase-8-independent component in TRAIL/Apo-2L-induced cell death in human rhabdomyosarcoma cells
Petak I, Vernes R, Szucs K, Anozie M, Izeradjene K, Douglas L, et al.
Cell Death Differ
. 2003 May;
10(6):729-39.
PMID: 12761581
Tumor necrosis factor related apoptosis inducing ligand (TRAIL) belongs to the Tumor necrosis factor (TNF) family of death-inducing ligands, and signaling downstream of TRAIL ligation to its receptor(s) remains to...
8.
Woollard K, Phillips D, Griffiths H
Clin Exp Immunol
. 2002 Oct;
130(2):256-62.
PMID: 12390313
C-reactive protein (CRP) is the prototypic acute phase serum protein in humans. The effects of CRP on primary human monocyte adhesion molecule expression and interaction with the endothelium have not...
9.
Acharya K, Stuart D, Phillips D, McKENZIE H, Teahan C
J Protein Chem
. 1994 Aug;
13(6):569-84.
PMID: 7832986
Similarities in amino acid sequences, three-dimensional structures, and the exon-intron patterns of their genes have indicated that c-type lysozymes and alpha-lactalbumins are homologous proteins, i.e., descended by divergent evolution from...
10.
Cheetham J, Artymiuk P, Phillips D
J Mol Biol
. 1992 Apr;
224(3):613-28.
PMID: 1569548
The structure of the tri-N-acetylchitotriose inhibitor complex of hen egg-white lysozyme has been refined at 1.75 A resolution, using data collected from a complex crystal with ligand bound at less...