D Biemesderfer
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Explore the profile of D Biemesderfer including associated specialties, affiliations and a list of published articles.
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46
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1223
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Recent Articles
1.
Biemesderfer D
Kidney Int
. 2006 Mar;
69(10):1717-21.
PMID: 16557231
Regulated intramembrane proteolysis (RIP) represents an evolutionarily conserved process linking receptor function with transcriptional regulation. Best characterized by the Notch signaling pathway, RIP involves regulated ectodomain shedding followed by gamma-secretase-mediated...
2.
Girardi A, Degray B, Nagy T, Biemesderfer D, Aronson P
J Biol Chem
. 2001 Oct;
276(49):46671-7.
PMID: 11590171
In an attempt to identify proteins that assemble with the apical membrane Na(+)-H(+) exchanger isoform NHE3, we generated monoclonal antibodies (mAbs) against affinity-purified NHE3 protein complexes isolated from solubilized renal...
3.
Douglas R, Schmitt B, Xia Y, Bevensee M, Biemesderfer D, Boron W, et al.
Neuroscience
. 2001 Feb;
102(1):217-28.
PMID: 11226686
We used western blotting to examine the developmental profiles (at embryonic day 16 and postnatal days 1, 13, 23, 33 and 105) of protein expression for three sodium-hydrogen exchanger isoforms...
4.
Mennone A, Biemesderfer D, Negoianu D, Yang C, Abbiati T, Schultheis P, et al.
Am J Physiol Gastrointest Liver Physiol
. 2001 Feb;
280(2):G247-54.
PMID: 11208547
Na+/H+ exchanger (NHE) isoforms play important roles in intracellular pH regulation and in fluid absorption. The isoform NHE3 has been localized to apical surfaces of epithelia and in some tissues...
5.
Bagnis C, Marsolais M, Biemesderfer D, LaPrade R, Breton S
Am J Physiol Renal Physiol
. 2001 Feb;
280(3):F426-36.
PMID: 11181404
An acidic luminal pH in the epididymis and vas deferens (VD) helps maintain mature sperm in an immotile state during storage. We have previously shown that the majority of proton...
6.
Biemesderfer D, DeGray B, Aronson P
J Biol Chem
. 2000 Dec;
276(13):10161-7.
PMID: 11120742
We have previously shown that Na(+)-H(+) exchanger isoform NHE3 exists as both 9.6 and 21 S (megalin-associated) oligomers in the renal brush border. To characterize the oligomeric forms of the...
7.
Peti-Peterdi J, Chambrey R, Bebok Z, Biemesderfer D, St John P, Abrahamson D, et al.
Am J Physiol Renal Physiol
. 2000 Mar;
278(3):F452-63.
PMID: 10710550
Functional and immunohistochemical studies were performed to localize and identify Na(+)/H(+) exchanger (NHE) isoforms in macula densa cells. By using the isolated perfused thick ascending limb with attached glomerulus preparation...
8.
Biemesderfer D, Nagy T, DeGray B, Aronson P
J Biol Chem
. 1999 Jun;
274(25):17518-24.
PMID: 10364184
We investigated whether the renal brush border Na+/H+ exchanger NHE3 exists in assemblies with other proteins in native kidney membranes. To this end we generated monoclonal antibodies (mAbs) against affinity...
9.
Schmitt B, Biemesderfer D, Romero M, Boulpaep E, Boron W
Am J Physiol
. 1999 Jan;
276(1):F27-38.
PMID: 9887077
Electrogenic cotransport of Na+ and HCO-3 is a crucial element of HCO-3 reabsorption in the renal proximal tubule (PT). An electrogenic Na+-HCO-3 cotransporter (NBC) has recently been cloned from salamander...
10.
Pizzonia J, Biemesderfer D, Abu-Alfa A, Wu M, Exner M, Isenring P, et al.
Am J Physiol
. 1998 Oct;
275(4):F510-7.
PMID: 9755122
Mammalian Na+/H+ exchangers (NHEs) are a family of transport proteins (NHE1-NHE5). To date, the cellular and subcellular localization of NHE4 has not been characterized using immunochemical techniques. We purified a...