A B Macdermott
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Explore the profile of A B Macdermott including associated specialties, affiliations and a list of published articles.
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41
Citations
1614
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Recent Articles
1.
Engelman H, Anderson R, Daniele C, Macdermott A
Neuroscience
. 2006 Feb;
139(2):539-53.
PMID: 16472927
Local inhibition within the spinal cord dorsal horn is mediated by the neurotransmitters GABA and glycine and strongly influences nociceptive and temperature signaling. Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are expressed by...
2.
Lee C, Labrakakis C, Joseph D, Macdermott A
Neuroscience
. 2004 Oct;
129(1):35-48.
PMID: 15489026
Dorsal root ganglion neurons express functional AMPA and kainate receptors near their central terminals. Activation of these receptors causes a decrease in glutamate release during action potential evoked synaptic transmission....
3.
Macdermott A
Neuron
. 2001 Nov;
32(3):376-8.
PMID: 11709147
Regulation of release of inhibitory neurotransmitter is a key element of plasticity in dorsal horn function. In this issue of Neuron, Kerchner et al. report that neurotransmitter release from inhibitory...
4.
Lee C, Kong H, Manzini M, Albuquerque C, Chao M, Macdermott A
J Neurosci
. 2001 Jun;
21(13):4572-81.
PMID: 11425885
Dorsal root ganglion (DRG) neurons first express kainate receptor subunits, predominantly GluR5, during embryonic development. In the DRG and throughout the nervous system, substantial editing of GluR5 mRNA occurs with...
5.
Labrakakis C, Gerstner E, Macdermott A
Neuroscience
. 2000 Dec;
101(4):1117-26.
PMID: 11113360
Sensory neurons express purinergic P2X receptors on their central and peripheral terminals as well as their cell bodies. ATP activation of these receptors drives action potential firing and glutamate release...
6.
Bardoni R, Magherini P, Macdermott A
Neuroreport
. 2000 Jun;
11(8):1721-7.
PMID: 10852232
We have investigated the role of NMDA receptors in mediating synaptic transmission in spinal cord lamina II over the first 2 weeks of postnatal development. High intensity root stimulation evoked...
7.
Albuquerque C, Lee C, Jackson A, Macdermott A
Eur J Neurosci
. 1999 Aug;
11(8):2758-66.
PMID: 10457172
Subpopulations of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors that are either permeable or impermeable to Ca2+ are expressed on dorsal horn neurons in culture. While both mediate synaptic transmission, the Ca2+ -permeable...
8.
Lee C, Engelman H, Macdermott A
Ann N Y Acad Sci
. 1999 Jul;
868:546-9.
PMID: 10414333
No abstract available.
9.
Macdermott A, Role L, Siegelbaum S
Annu Rev Neurosci
. 1999 Apr;
22:443-85.
PMID: 10202545
The quantity of neurotransmitter released into the synaptic cleft, the reliability with which it is released, and the response of the postsynaptic cell to that transmitter all contribute to the...
10.
Engelman H, Allen T, Macdermott A
J Neurosci
. 1999 Mar;
19(6):2081-9.
PMID: 10066261
The superficial dorsal horn is a major site of termination of nociceptive primary afferents. Fast excitatory synaptic transmission in this region is mediated mainly by release of glutamate onto postsynaptic...