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D Avni

Explore the profile of D Avni including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 10
Citations 413
Followers 0
Related Specialties
Oncology
Molecular Biology
Biochemistry
Top 10 Co-Authors
O Meyuhas
S Shama
J Jacob-Hirsch
Y Sidi
R Leibowitz-Amit
R Berger
Z C Zhang
T Meningher
A Israel
E Razin
Published In
Oncogene
Proc Natl Acad Sci U S A
Nucleic Acids Res
Br J Dermatol
Gene Expr
Affiliations
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Recent Articles
1.
Alterations of microRNAs throughout the malignant evolution of cutaneous squamous cell carcinoma: the role of miR-497 in epithelial to mesenchymal transition of keratinocytes
Mizrahi A, Barzilai A, Gur-Wahnon D, Ben-Dov I, Glassberg S, Meningher T, et al.
Oncogene . 2017 Sep; 37(2):218-230. PMID: 28925390
Skin carcinogenesis is known to be a multi-step process with several stages along its malignant evolution. We hypothesized that transformation of normal epidermis to cutaneous squamous cell carcinoma (cSCC) is...
2.
Association between the Absolute Baseline Lymphocyte Count and Response to Neoadjuvant Platinum-based Chemotherapy in Muscle-invasive Bladder Cancer
Leibowitz-Amit R, Israel A, Gal M, Atenafu E, Symon Z, Portnoy O, et al.
Clin Oncol (R Coll Radiol) . 2016 Aug; 28(12):790-796. PMID: 27498850
Aims: Platinum-based neoadjuvant chemotherapy (NAC) improves overall survival in muscle-invasive bladder cancer (MIBC). A pathological complete response (pCR) at radical cystectomy after NAC is associated with better overall survival, but...
3.
The phosphorylated prodrug FTY720 is a histone deacetylase inhibitor that reactivates ERα expression and enhances hormonal therapy for breast cancer
Hait N, Avni D, Yamada A, Nagahashi M, Aoyagi T, Aoki H, et al.
Oncogenesis . 2015 Jun; 4:e156. PMID: 26053034
Estrogen receptor-α (ERα)-negative breast cancer is clinically aggressive and does not respond to conventional hormonal therapies. Strategies that lead to re-expression of ERα could sensitize ERα-negative breast cancers to selective...
4.
Small-interfering RNA targeted at antiapoptotic mRNA increases keratinocyte sensitivity to apoptosis
Lerman G, Volman E, Sidi Y, Avni D
Br J Dermatol . 2010 Dec; 164(5):947-56. PMID: 21166662
Background: Gene silencing RNA interference technology concentrates on downregulation of gene expression using specific double-stranded RNA molecules (small-interfering RNA, siRNA), which induce the degradation of complementary mRNA. SiRNA therapeutics is...
5.
The expression of poly(A)-binding protein gene is translationally regulated in a growth-dependent fashion through a 5'-terminal oligopyrimidine tract motif
Hornstein E, Git A, Braunstein I, Avni D, Meyuhas O
J Biol Chem . 1999 Jan; 274(3):1708-14. PMID: 9880551
Poly(A)-binding protein (PABP) is an important regulator of gene expression that has been implicated in control of translation initiation. Here we report the isolation and the initial structural and functional...
6.
Growth-dependent and PKC-mediated translational regulation of the upstream stimulating factor-2 (USF2) mRNA in hematopoietic cells
Zhang Z, Nechushtan H, Jacob-Hirsch J, Avni D, Meyuhas O, Razin E
Oncogene . 1998 Mar; 16(6):763-9. PMID: 9488040
Upstream stimulating factor (USF2) is a basic helix-loop-helix leucine zipper transcription factor, which is found in most tissues. A critical role for USF2 in cellular proliferation has been proposed based...
7.
The 5' terminal oligopyrimidine tract confers translational control on TOP mRNAs in a cell type- and sequence context-dependent manner
Avni D, Biberman Y, Meyuhas O
Nucleic Acids Res . 1997 Mar; 25(5):995-1001. PMID: 9023110
TOP mRNAs are vertebrate transcripts which contain a 5'terminal oligopyrimidine tract (5'TOP), encode for ribosomal proteins and elongation factors 1alpha and 2, and are candidates for growth-dependent translational control mediated...
8.
Overexpression of initiation factor eIF-4E does not relieve the translational repression of ribosomal protein mRNAs in quiescent cells
Shama S, Avni D, Frederickson R, Sonenberg N, Meyuhas O
Gene Expr . 1995 Jan; 4(4-5):241-52. PMID: 7787416
Translation of ribosomal protein (rp) mRNA is selectively repressed in mouse erythroleukemia (MEL) cells, which cease to proliferate upon differentiation, and in NIH 3T3 cells, for which growth is arrested...
9.
Vertebrate mRNAs with a 5'-terminal pyrimidine tract are candidates for translational repression in quiescent cells: characterization of the translational cis-regulatory element
Avni D, Shama S, Loreni F, Meyuhas O
Mol Cell Biol . 1994 Jun; 14(6):3822-33. PMID: 8196625
The translation of mammalian ribosomal protein (rp) mRNAs is selectively repressed in nongrowing cells. This response is mediated through a regulatory element residing in the 5' untranslated region of these...
10.
Oligopyrimidine tract at the 5' end of mammalian ribosomal protein mRNAs is required for their translational control
Levy S, Avni D, Hariharan N, PERRY R, Meyuhas O
Proc Natl Acad Sci U S A . 1991 Apr; 88(8):3319-23. PMID: 2014251
Mammalian ribosomal protein (rp) mRNAs are subject to translational control, as illustrated by their selective release from polyribosomes in growth-arrested cells and their underrepresentation in polysomes in normally growing cells....