D Alexoff
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Explore the profile of D Alexoff including associated specialties, affiliations and a list of published articles.
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20
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570
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Recent Articles
1.
Volkow N, Wang G, Logan J, Alexoff D, Fowler J, Thanos P, et al.
Transl Psychiatry
. 2015 Apr;
5:e549.
PMID: 25871974
Caffeine, the most widely consumed psychoactive substance in the world, is used to promote wakefulness and enhance alertness. Like other wake-promoting drugs (stimulants and modafinil), caffeine enhances dopamine (DA) signaling...
2.
Volkow N, Tomasi D, Wang G, Fowler J, Telang F, Goldstein R, et al.
Mol Psychiatry
. 2011 Apr;
16(8):818-25.
PMID: 21483434
Positive emotionality (PEM) (personality construct of well-being, achievement/motivation, social and closeness) has been associated with striatal dopamine D2 receptor availability in healthy controls. As striatal D2 receptors modulate activity in...
3.
Fowler J, Logan J, Ding Y, Franceschi D, Wang G, Volkow N, et al.
J Neurochem
. 2001 Dec;
79(5):1039-46.
PMID: 11739617
Clorgyline is an irreversible inhibitor of monoamine oxidase (MAO A) which has been labeled with carbon-11 (C-11) and used to measure human brain MAO A with positron emission tomography (PET)....
4.
Fowler J, Ding Y, Logan J, MacGregor R, Shea C, Garza V, et al.
Nucl Med Biol
. 2001 Oct;
28(7):779-85.
PMID: 11578898
[11C]Clorgyline selectively binds to MAO A in the human brain. This contrasts with a recent report that [11C]clorgyline (in contrast to other labeled MAO A inhibitors) is not retained in...
5.
Volkow N, Wang G, Fowler J, Franceschi D, Thanos P, Wong C, et al.
Life Sci
. 2000 Mar;
66(12):PL161-7.
PMID: 10737368
Unlabelled: Cocaine and alcohol are frequently used simultaneously and this combination is associated with enhanced toxicity. We recently showed that active cocaine abusers have a markedly enhanced sensitivity to benzodiazepines....
6.
Fowler J, Volkow N, Wang G, Pappas N, Logan J, MacGregor R, et al.
J Addict Dis
. 1998 Apr;
17(1):23-34.
PMID: 9549600
We measured the concentration of brain monoamine oxidase B (MAO B; EC 1.4.3.4) in 8 smokers and compared it with that in 8 non-smokers and in 4 former smokers using...
7.
Schlosser R, BRODIE J, Dewey S, Alexoff D, Wang G, Fowler J, et al.
Synapse
. 1997 Dec;
28(1):66-70.
PMID: 9414019
There is evidence for the shift of regulatory setpoints of functionally linked neurotransmitter systems as a basis of psychiatric disorders. 11C-raclopride PET, which has been shown to be sensitive to...
8.
Fowler J, Volkow N, Wang G, Pappas N, Logan J, Shea C, et al.
Proc Natl Acad Sci U S A
. 1996 Nov;
93(24):14065-9.
PMID: 8943061
Several studies have documented a strong association between smoking and depression. Because cigarette smoke has been reported to inhibit monoamine oxidase (MAO) A in vitro and in animals and because...
9.
Wang G, Volkow N, Levy A, Fowler J, Logan J, Alexoff D, et al.
J Comput Assist Tomogr
. 1996 May;
20(3):423-8.
PMID: 8626905
Purpose: Our goal was to assess the utility of MR-PET image coregistration to quantify dopamine D2 receptors in striatum. Method: Twenty-nine normal subjects were investigated with PET and [11C]raclopride and...
10.
Fowler J, Volkow N, Wang G, Pappas N, Logan J, MacGregor R, et al.
Nature
. 1996 Feb;
379(6567):733-6.
PMID: 8602220
The massive health problem associated with cigarette smoking is exacerbated by the addictive properties of tobacco smoke and the limited success of current approaches to cessation of smoking. Yet little...