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D Alexoff

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11.
Dewey S, Smith G, Logan J, Alexoff D, Ding Y, King P, et al.
J Neurosci . 1995 Jan; 15(1 Pt 2):821-9. PMID: 7823183
Positron emission tomography and in vivo microdialysis were used to study serotonin's role in modulating striatal dopamine. Serial PET studies were performed in adult female baboons at baseline and following...
12.
Fowler J, Volkow N, Logan J, Wang G, MacGregor R, Schyler D, et al.
Synapse . 1994 Oct; 18(2):86-93. PMID: 7839316
L-Deprenyl (Selegeline) is an enzyme-activated irreversible inhibitor of monoamine oxidase B (MAO B; EC 1.4.3.4). It is used to treat Parkinson's disease at a dose of 5 mg twice a...
13.
Ding Y, Fowler J, Volkow N, Gatley S, Logan J, Dewey S, et al.
Synapse . 1994 Oct; 18(2):152-60. PMID: 7839313
dl-threo-Methylphenidate (Ritalin) was labeled with carbon-11 (t1/2:20.4 minutes) in order to measure its pharmacokinetics, to evaluate it as a radiotracer for the presynaptic dopaminergic neuron, and to examine its sensitivity...
14.
Fowler J, Ding Y, Volkow N, Martin T, MacGregor R, Dewey S, et al.
Synapse . 1994 Apr; 16(4):312-7. PMID: 8059340
Positron emission tomography (PET), [11C]cocaine, and (-)-6-[18F]fluoronorepinephrine [(-)-6-[18F]NE] were used to determine the extent to which the binding of labeled cocaine in the baboon heart represents binding to the norepinephrine...
15.
Wang G, Volkow N, Fowler J, Ferrieri R, Schlyer D, Alexoff D, et al.
Life Sci . 1994 Jan; 54(9):PL143-6. PMID: 8114609
To assess the effects of methylphenidate (MP) on cerebral blood flow (CBF), 5 healthy males were studied using 15O-water and positron emission tomography before and after MP (0.5 mg/kg iv)....
16.
Fowler J, Volkow N, Logan J, Schlyer D, MacGregor R, Wang G, et al.
Neurology . 1993 Oct; 43(10):1984-92. PMID: 8413955
The possibility of slowing the progression of Parkinson's disease (PD) with inhibitors of monoamine oxidase B (MAO B) has stimulated the development of new MAO B inhibitor drugs. Ro 19...
17.
Volkow N, Fowler J, Wang G, Dewey S, Schlyer D, MacGregor R, et al.
J Nucl Med . 1993 Apr; 34(4):609-13. PMID: 8455077
Carbon-11-raclopride has been successfully utilized with PET to assess changes in endogenous dopamine concentration after pharmacological intervention in the living baboon brain. For similar studies to be done in humans,...
18.
Schlyer D, BASTOS M, Alexoff D, Wolf A
Int J Rad Appl Instrum A . 1990 Jan; 41(6):531-3. PMID: 2163371
The separation of no carrier added [18F]fluoride from 18O enriched water is described. The [18F]fluoride is deposited on Dowex 1 x 10 anion exchange resin as the water is passed...
19.
Alexoff D, Schlyer D, Wolf A
Int J Rad Appl Instrum A . 1989 Jan; 40(1):1-6. PMID: 2540119
The recovery of [18F]fluoride from [18O]water using an electric field to deposit and remove the fluoride is described. An electrolytic cell was constructed to study [18F]fluoride recovery as a function...
20.