D A Owensby
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Explore the profile of D A Owensby including associated specialties, affiliations and a list of published articles.
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21
Citations
205
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Recent Articles
1.
Grimsley P, Quinn K, Owensby D
Trends Cardiovasc Med
. 2004 Feb;
8(8):363-8.
PMID: 14987551
Soluble forms of receptors can influence the activity of their membrane-bound counterparts by affecting their interactions with ligands. Low density lipoprotein (LDL) receptor-related protein (LRP), a member of the LDL...
2.
Quinn K, Pye V, Dai Y, Chesterman C, Owensby D
Exp Cell Res
. 1999 Sep;
251(2):433-41.
PMID: 10471328
We report characterization of the soluble form of the low density lipoprotein receptor-related protein (sLRP) which circulates in human plasma. Amino acid sequence analysis confirmed that sLRP isolated from human...
3.
Grimsley P, Quinn K, Chesterman C, Owensby D
Thromb Res
. 1999 May;
94(3):153-64.
PMID: 10326762
Low density lipoprotein receptor family members characteristically bind 39-kDa receptor associated protein (RAP). Soluble forms of these receptors have been described in humans including the 515/85-kDa dimeric receptor, low density...
4.
Grimsley P, Quinn K, Chesterman C, Owensby D
Thromb Res
. 1998 Jun;
88(6):485-98.
PMID: 9610960
The multiligand receptor, low density lipoprotein receptor-related protein (LRP), is implicated in processes such as atherosclerosis and fibrinolysis through its mediation of the catabolism of lipoproteins, proteases, and protease inhibitor...
5.
Quinn K, Grimsley P, Dai Y, Tapner M, Chesterman C, Owensby D
J Biol Chem
. 1997 Sep;
272(38):23946-51.
PMID: 9295345
Our studies have identified a soluble molecule in normal human plasma and serum with the characteristics of the alpha-chain of the low density lipoprotein receptor-related protein (LRP). LRP is a...
6.
Grimsley P, Normyle J, Brandt R, Joulianos G, Chesterman C, Hogg P, et al.
Thromb Res
. 1995 Aug;
79(4):353-61.
PMID: 7482438
The adherent human hepatoma cell line Hep G2 exhibits receptor mediated endocytosis and catabolism of tissue-type plasminogen activator.plasminogen activator inhibitor type-1 (t-PA.PAI-1) complexes formed when exogenous t-PA combines with endogenous...
7.
Hogg P, Owensby D, Chesterman C
J Biol Chem
. 1993 Oct;
268(29):21811-8.
PMID: 8408036
Thrombospondin 1 was recently shown to bind to and inhibit the activity of neutrophil elastase (Hogg, P. J., Owensby, D. A., Mosher, D. F., Misenheimer, T. M., and Chesterman, C....
8.
Hogg P, Owensby D, Mosher D, Misenheimer T, Chesterman C
J Biol Chem
. 1993 Apr;
268(10):7139-46.
PMID: 8463250
Thrombospondin, a glycoprotein of three identical disulfide-bonded subunits, is a constituent of platelet alpha-granules and a variety of normal and transformed cells and binds to cell surfaces and becomes incorporated...
9.
Underhill D, Owensby D, Morton P, Schwartz A
Blood
. 1992 Dec;
80(11):2746-54.
PMID: 1333299
Receptor-mediated endocytosis of tissue-type plasminogen activator (t-PA)-plasminogen activator inhibitor type 1 (PAI-1) complexes results in their clearance by Hep G2 cells. After complexes are internalized, the t-PA component is degraded....
10.
Khachigian L, Owensby D, Chesterman C
J Biol Chem
. 1992 Jan;
267(3):1660-6.
PMID: 1309790
Platelet-derived growth factor (PDGF) is a potent mitogen for cells of mesenchymal origin. Alternative exon splicing is responsible for two forms of the PDGF A-chain which differ at the carboxyl...