D A DAlessio
Overview
Explore the profile of D A DAlessio including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
32
Citations
915
Followers
0
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Recent Articles
1.
El K, Gray S, Capozzi M, Knuth E, Jin E, Svendsen B, et al.
Sci Adv
. 2021 Mar;
7(11).
PMID: 33712466
Glucose-dependent insulinotropic polypeptide (GIP) communicates nutrient intake from the gut to islets, enabling optimal levels of insulin secretion via the GIP receptor (GIPR) on β cells. The GIPR is also...
2.
Gilroy C, Capozzi M, Varanko A, Tong J, DAlessio D, Campbell J, et al.
Sci Adv
. 2020 Sep;
6(35):eaaz9890.
PMID: 32923621
There is great interest in identifying a glucagon-like peptide-1 (GLP-1)-based combination therapy that will more effectively promote weight loss in patients with type 2 diabetes. Fibroblast growth factor 21 (FGF21)...
3.
Strawn J, DAlessio D, Keck Jr P, Seeley R
J Psychiatr Res
. 2007 Sep;
42(9):787-9.
PMID: 17888452
The insulin secretogogue glucagon like peptide-1 (GLP-1), as well as agents which enhance GLP-1 signaling, are being studied as potential treatments for diabetes. Pre-clinical evidence suggests that these agents may...
4.
Pfluger P, Kampe J, Castaneda T, Vahl T, DAlessio D, Kruthaupt T, et al.
J Clin Endocrinol Metab
. 2006 Nov;
92(2):583-8.
PMID: 17119001
Background: Recent findings suggest that low plasma peptide YY (PYY) levels may contribute to diet-induced human obesity and justify PYY replacement therapy. Although the pharmacological value of PYY is controversial,...
5.
Ehlers M, Klaff L, DAlessio D, Brazg R, Kay H, Harley R, et al.
Horm Metab Res
. 2003 Nov;
35(10):611-6.
PMID: 14605997
Aims: To evaluate the safety and efficacy of various doses of recombinant glucagon-like peptide-1 (7-36) amide (rGLP-1) administered subcutaneously (s. c.) via bolus injection or continuous infusion to lower fasting...
6.
Henchoz E, DAlessio D, Gillet M, Halkic N, Matzinger O, Goy J, et al.
Transplantation
. 2003 Sep;
76(6):923-9.
PMID: 14508355
Background: The prevalence of diabetes is high after transplantation. We hypothesized that liver transplantation induces additional alterations of glucose homeostasis because of liver denervation. Methods: Nondiabetic patients with a heart...
7.
Rushing P, Hagan M, Seeley R, Lutz T, DAlessio D, Air E, et al.
Endocrinology
. 2001 Oct;
142(11):5035.
PMID: 11606473
Amylin is a 37-amino acid peptide hormone that is co-secreted with insulin by pancreatic beta cells in response to feeding. We recently reported that amylin potently reduces food intake, body...
8.
DAlessio D, Kieffer T, Taborsky Jr G, Havel P
J Clin Endocrinol Metab
. 2001 Mar;
86(3):1253-9.
PMID: 11238517
Meal-induced insulin secretion is thought to be regulated primarily by absorbed nutrients and incretin hormones released from the gastrointestinal tract. In addition, the parasympathetic nervous system (PNS) is known to...
9.
Verchere C, DAlessio D, Prigeon R, Hull R, Kahn S
Diabetes
. 2000 Sep;
49(9):1477-84.
PMID: 10969831
Islet amyloid polypeptide (IAPP or amylin) is a normal secretory product of the pancreatic beta-cell that is cosecreted with insulin and is the major constituent of islet amyloid deposits in...
10.
Owen O, Smalley K, DAlessio D, Mozzoli M, Dawson E
Am J Clin Nutr
. 1998 Jul;
68(1):12-34.
PMID: 9665093
The purpose of this work was to clarify the essentiality of glucose production from amino acids in obese subjects undergoing prolonged starvation and to provide an explanation for death after...