Cynthia Tremblay
Overview
Explore the profile of Cynthia Tremblay including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
130
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0
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Recent Articles
1.
Boisvert O, Letourneau D, Delattre P, Tremblay C, Jolibois E, Montagne M, et al.
Structure
. 2021 Dec;
30(4):623-636.e5.
PMID: 34963061
Miz-1 (ZBTB17) is a poly-zinc finger BTB/POZ transcription factor with 12 consecutive C2H2 zinc fingers (ZFs) that binds transcriptional start sites (TSSs) to regulate the expression of genes involved in...
2.
Bosoi C, Vandal M, Tournissac M, Leclerc M, Fanet H, Mitchell P, et al.
Hepatol Commun
. 2021 Mar;
5(3):446-460.
PMID: 33681678
Obesity and diabetes are strongly associated not only with fatty liver but also cognitive dysfunction. Moreover, their presence, particularly in midlife, is recognized as a risk factor for Alzheimer's disease...
3.
Beaulieu M, Jauset T, Masso-Valles D, Martinez-Martin S, Rahl P, Maltais L, et al.
Sci Transl Med
. 2019 Mar;
11(484).
PMID: 30894502
Inhibiting MYC has long been considered unfeasible, although its key role in human cancers makes it a desirable target for therapeutic intervention. One reason for its perceived undruggability was the...
4.
Maltais L, Montagne M, Bedard M, Tremblay C, Soucek L, Lavigne P
PLoS One
. 2017 Mar;
12(3):e0174413.
PMID: 28350847
It is classically recognized that the physiological and oncogenic functions of Myc proteins depend on specific DNA binding enabled by the dimerization of its C-terminal basic-region-Helix-Loop-Helix-Leucine Zipper (b-HLH-LZ) domain with...
5.
Tremblay C, Bedard M, Bonin M, Lavigne P
Biochem Biophys Res Commun
. 2016 Mar;
473(2):471-5.
PMID: 26972249
Miz-1 is a BTB/POZ transcription factor that contains 13C2H2 Zinc Finger domains (ZF). Miz-1 transactivates and represses the transcription of a myriad of genes involved in many aspects of the...