Cynthia A Berlinicke
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Explore the profile of Cynthia A Berlinicke including associated specialties, affiliations and a list of published articles.
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28
Citations
778
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Recent Articles
1.
Sripathi S, Hu M, Turaga R, Mikeasky R, Satyanarayana G, Cheng J, et al.
Cells
. 2023 May;
12(8).
PMID: 37190063
Epithelial-mesenchymal transition (EMT), which is well known for its role in embryonic development, malignant transformation, and tumor progression, has also been implicated in a variety of retinal diseases, including proliferative...
2.
Pantoja I, Smirnova L, Muotri A, Wahlin K, Kahn J, Boyd J, et al.
Front Artif Intell
. 2023 Mar;
6:1116870.
PMID: 36925616
The brain is arguably the most powerful computation system known. It is extremely efficient in processing large amounts of information and can discern signals from noise, adapt, and filter faulty...
3.
Maestas Jr D, Chung L, Han J, Wang X, Sommerfeld S, Kelly S, et al.
Proc Natl Acad Sci U S A
. 2023 Feb;
120(8):e2211703120.
PMID: 36780522
The immune system is increasingly recognized as an important regulator of tissue repair. We developed a regenerative immunotherapy from the helminth soluble egg antigen (SEA) to stimulate production of interleukin...
4.
Zhang P, Zhang S, Li W, Keuthan C, Li S, Takaesu F, et al.
EBioMedicine
. 2022 Aug;
83:104225.
PMID: 36030648
Background: Though case fatality rate (CFR) is widely used to reflect COVID-19 fatality risk, its use is limited by large temporal and spatial variation. Hospital mortality rate (HMR) is also...
5.
Rui Y, Wilson D, Tzeng S, Yamagata H, Sudhakar D, Conge M, et al.
Sci Adv
. 2022 Jan;
8(1):eabk2855.
PMID: 34985952
Nanoparticle-based mRNA therapeutics hold great promise, but cellular internalization and endosomal escape remain key barriers for cytosolic delivery. We developed a dual nanoparticle uptake and endosomal disruption assay using high-throughput...
6.
Sripathi S, Hu M, Turaga R, Mertz J, Liu M, Wan J, et al.
Mol Cell Proteomics
. 2021 Aug;
20:100131.
PMID: 34455105
Stress and injury to the retinal pigment epithelium (RPE) often lead to dedifferentiation and epithelial-to-mesenchymal transition (EMT). These processes have been implicated in several retinal diseases, including proliferative vitreoretinopathy, diabetic...
7.
Hu Y, Zhu Y, Sutherland N, Wilson D, Pang M, Liu E, et al.
Nano Lett
. 2021 Jul;
21(13):5697-5705.
PMID: 34228937
Polyelectrolyte complex particles assembled from plasmid DNA (pDNA) and poly(ethylenimine) (PEI) have been widely used to produce lentiviral vectors (LVVs) for gene therapy. The current batch-mode preparation for pDNA/PEI particles...
8.
Hsueh H, Kim Y, Pitha I, Shin M, Berlinicke C, Chou R, et al.
Pharmaceutics
. 2021 Jun;
13(5).
PMID: 34062883
Glaucoma is the leading cause of irreversible blindness worldwide. Elevated intraocular pressure (IOP) is one of the major risk factors for glaucoma onset and progression, and available pharmaceutical interventions are...
9.
Kim Y, Hsueh H, Shin M, Berlinicke C, Han H, Anders N, et al.
Drug Deliv Transl Res
. 2021 Apr;
12(4):826-837.
PMID: 33900546
While eye drops are the most common ocular dosage form, eye drops for treating diseases of the posterior segment (retina, choroid, optic nerve) have yet to be developed. In glaucoma,...
10.
Sripathi S, Hu M, Liu M, Wan J, Cheng J, Duan Y, et al.
Invest Ophthalmol Vis Sci
. 2021 Apr;
62(4):1.
PMID: 33792620
Purpose: RPE injury often induces epithelial to mesenchymal transition (EMT). Although RPE-EMT has been implicated in a variety of retinal diseases, including proliferative vitroretinopathy, neovascular and atrophic AMD, and diabetic...