Curtis J Mello
Overview
Explore the profile of Curtis J Mello including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
112
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0
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Recent Articles
1.
Wells M, Nemesh J, Ghosh S, Mitchell J, Salick M, Mello C, et al.
Cell Stem Cell
. 2023 Feb;
30(3):312-332.e13.
PMID: 36796362
Human genome variation contributes to diversity in neurodevelopmental outcomes and vulnerabilities; recognizing the underlying molecular and cellular mechanisms will require scalable approaches. Here, we describe a "cell village" experimental platform...
2.
Limone F, Guerra San Juan I, Mitchell J, Smith J, Raghunathan K, Meyer D, et al.
Cell Rep
. 2023 Jan;
42(1):111896.
PMID: 36596304
Human pluripotent stem cells (hPSCs) are a powerful tool for disease modeling of hard-to-access tissues (such as the brain). Current protocols either direct neuronal differentiation with small molecules or use...
3.
Genovese G, Mello C, Loh P, Handsaker R, Kashin S, Whelan C, et al.
Sci Rep
. 2022 Jul;
12(1):12025.
PMID: 35835769
Non-invasive prenatal testing (NIPT) to detect fetal aneuploidy by sequencing the cell-free DNA (cfDNA) in maternal plasma is being broadly adopted. To detect fetal aneuploidies from maternal plasma, where fetal...
4.
Leung A, Bell A, Mello C, Penzias A, McCarroll S, Sakkas D
J Assist Reprod Genet
. 2021 Aug;
38(11):2975-2983.
PMID: 34417660
Purpose: This pilot study sought to (1) validate the use of a novel technology for single-sperm-cell genome sequencing (Sperm-seq) in infertile men who may not have optimal quantity or quality...
5.
Bell A, Mello C, Nemesh J, Brumbaugh S, Wysoker A, McCarroll S
Nature
. 2020 Jun;
583(7815):259-264.
PMID: 32494014
Meiosis, although essential for reproduction, is also variable and error-prone: rates of chromosome crossover vary among gametes, between the sexes, and among humans of the same sex, and chromosome missegregation...